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170720s2017 xxu| s |||| 0|eng d |
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|a 9781493971541
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| 024 |
7 |
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|a 10.1007/978-1-4939-7154-1
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Kinase Signaling Networks /
|c edited by Aik-Choon Tan, Paul H. Huang.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2017.
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| 300 |
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|a XVII, 537 p. 112 illus., 74 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1636
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| 505 |
0 |
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|a Optogenetic Control of Ras/Erk Signaling Using the Phy–PIF System -- Dissecting Kinase Effector Signaling Using the RapRTAP Methodology -- Single-Cell Imaging of ERK Signaling Using Fluorescent Biosensors -- Quantification of Cell Signaling Networks Using Kinase Activity Chemosensors -- Expression of Recombinant Phosphoproteins for Signal Transduction Studies -- Allosteric Modulation of Src-Family Kinases with ATP-Competitive Inhibitors -- Characterization of Ligand Binding to Pseudokinases Using a Thermal Shift Assay -- Proteomic Profiling of Protein Kinase Inhibitor Targets by Mass Spectrometry -- Utilizing the Luminex Magnetic Bead-Based Suspension Arrays for Rapid Multiplexed Phosphoprotein Quantification -- High-Content Imaging and RNAi Screens for Investigating Kinase Network Plasticity -- Analysis of Drug Resistance Using Kinome-Wide Functional Screens -- Identification and Validation of Driver Kinases from Next Generation Sequencing Data -- Label-Free Phosphoproteomic Approach for Kinase Signaling Analysis -- Cell-Specific Labeling for Analyzing Bidirectional Signaling by Mass Spectrometry -- Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics -- Analysis of Phosphotyrosine Signaling Networks in Lung Cancer Cell Lines -- Targeted Analysis of Phosphotyrosine Signaling by Multiple-Reaction-Monitoring Mass Spectrometry -- Phosphoproteomic Analysis of Isolated Mitochondria in Yeast -- A Methodology for Comprehensive Analysis of Toll-Like Receptor Signaling in Macrophages -- Absolute Phosphorylation Stoichiometry Analysis by Motif-Targeting Quantitative Mass Spectrometry -- Identification of Plant Kinase Substrates Based on Kinase Assay-Linked Phosphoproteomics -- Mass Spectrometry Analysis of Spatial Protein Networks by Colocalization Analysis (COLA) -- Development of Selected Reaction Monitoring Methods to Systematically Quantify Kinase Abundance and Phosphorylation Stoichiometry in Human Samples -- Analysis of Signaling Networks at the Single Cell Level Using Mass Cytometry -- Magnetic Resonance Spectroscopy (MRS)-Based Methods for Examining Cancer Metabolism in Response to Oncogenic Kinases Drug Treatment -- Deconstructing the Metabolic Networks of Oncogenic Signaling Using Targeted Liquid-Chromatography Tandem Mass Spectrometry (LC-MS/MS) -- Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols -- An Interdisciplinary Approach for Designing Kinetic Models of the Ras/MAPK Signaling Pathway -- Databases and Computational Tools for Evolutionary Analysis of Protein Phosphorylation -- Informatics Approaches for Predicting, Understanding, and Testing Cancer Drug Combinations -- Target Inhibition Maps Based on Responses to Kinase Inhibitors -- Partial Least Squares Regression Models for the Analysis of Kinase Signaling.
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| 650 |
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|a Biochemistry.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 700 |
1 |
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|a Tan, Aik-Choon.
|e editor.
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| 700 |
1 |
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|a Huang, Paul H.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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