Imaging in Drug Discovery and Early Clinical Trials /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Basel :
Birkhäuser Basel : Imprint: Birkhäuser,
2005.
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| Edición: | 1st ed. 2005. |
| Colección: | Progress in Drug Research,
62 |
| Materias: |
Tabla de Contenidos:
- The drug discovery process
- Imaging modalities: principles and information content
- Magnetic resonance and fluorescence based molecular imaging technologies
- Studying molecular and cellular processes in the intact organism
- Disease phenotyping: structural and functional readouts
- Evaluation of drug candidates: Efficacy readouts during lead optimization
- Risk identification and management: MRI as a research tool in toxicology studies of new chemical entities
- Pharmacokinetic studies with PET
- Imaging bio-markers predictive of disease/therapy outcome: ischemic stroke and drug development
- Clinical drug evaluation using imaging readouts: regulatory perspectives.