Huntington's Disease /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Precious, Sophie V. (Editor ), Rosser, Anne E. (Editor ), Dunnett, Stephen B. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2018.
Edición:1st ed. 2018.
Colección:Methods in Molecular Biology, 1780
Materias:
Tabla de Contenidos:
  • Stereological Methods to Quantify Cell Loss in the Huntington's Disease Human Brain
  • Assessing Autophagic Activity and Aggregate Formation of Mutant Huntingtin in Mammalian Cells
  • A Filter Retardation Assay Facilitates the Detection and Quantification of Heat-Stable, Amyloidogenic Mutant Huntingtin Aggregates in Complex Biosamples
  • Cellular Models: HD Patient-Derived Pluripotent Stem Cells
  • Non-Mammalian Models of Huntington's Disease
  • Mouse Models of Huntington's Disease
  • Motor Assessment in Huntington's Disease Mice
  • Automated Operant Assessments of Huntington's Disease Mouse Models
  • Neurophysiological Assessment of Huntington's Disease Model Mice
  • Murine Models of Huntington's Disease for Evaluating Therapeutics
  • Generating Excitotoxic Lesion Models of Huntington's Disease
  • Large-Brained Animal Models of Huntington's Disease: Sheep
  • Minipigs as Large-Brained Animal Model for Huntington's Disease: From Behavior and Imaging to Gene Therapy
  • Non-Human Primate Models of Huntington's Disease and Their Application in Translational Research
  • In Vivo Multidimensional Brain Imaging in Huntington's Disease Animal Models
  • Magnetic Resonance Imaging in Huntington's Disease
  • Biofluid Biomarkers in Huntington's Disease
  • Assessing and Modulating Kynurenine Pathway Dynamics in Huntington's Disease: Focus on Kynurenine 3-Monooxygenase
  • Assessing Mitochondrial Function in In Vitro and Ex Vivo Models of Huntington's Disease
  • Using Genomic Data to Find Disease-Modifying Loci in Huntington's Disease (HD).-CRISPR/Cas9-Mediated Genome Editing for Huntington's Disease
  • Methods for Assessing DNA Repair and Repeat Expansion in Huntington's Disease
  • Translating Antisense Technology into a Treatment for Huntington's Disease
  • Disease Modification through Trophic Factor Delivery
  • Methods to Quantify Cell Signaling and GPCR Receptor Ligand Bias: Characterization of Drugs that Target the Endocannabinoid Receptors in Huntington's Disease
  • Dissection and Preparation of Human Primary Fetal Ganglionic Eminence Tissue for Research and Clinical Application
  • Robust Induction of DARPP32-Expressing GABAergic Striatal Neurons from Human Pluripotent Stem Cells
  • Quality Assessment and Production of Human Cells for Clinical Use.