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100301s2009 ne | s |||| 0|eng d |
| 020 |
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|a 9781402090639
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| 024 |
7 |
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|a 10.1007/978-1-4020-9063-9
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Handbook on Immunosenescence :
|b basic understanding and clinical applications /
|c edited by Tamas Fulop, Claudio Franceschi, Katsuiki Hirokawa, Graham Pawelec.
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| 250 |
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|a 1st ed. 2009.
|
| 260 |
# |
# |
|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2009.
|
| 300 |
|
|
|a XXXI, 1655 p. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
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|a online resource
|b cr
|2 rdacarrier
|
| 505 |
0 |
|
|a 1. Immunosenescence -- 2. Methods and models for studying immunosenescence -- 3. Cellular immunosenescence. 3.1 T cells. 3.2. B cells. 3.3 Neutrophils. 3.4 Antigen presenting cells. 3.5 NK and NKT cells. 3.6. Stem cells. 3.7. Genetics -- 4. Mechanisms 4.1. Receptors and signal transduction. 4.2 Mitochondria. 4.3 Proteasome. 4.4 Cytokines. 4.5 Neuro-endocrine-immune Network. 4.6 Thymus. 4.7. Inflammation -- 5. Clinical relevance in disease states. 5.1 Infection. 5.2 Autoimmunity. 5.3 Cancer. 5.4 Metabolic syndrome. 5.5. Neurodegenerative diseases. 5.6 Frailty. 5.7. Osteoporosis -- 6. Modulation. 6.1 Nutrition. 6.2. Lipids. 6.3. Vaccination. 6.4. Can interventions to influence immunosenescence succeed? Subject Index.
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| 650 |
|
0 |
|a Medicine.
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| 650 |
|
0 |
|a Immunology.
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| 650 |
|
0 |
|a Geriatrics.
|
| 650 |
1 |
4 |
|a Biomedicine, general.
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| 650 |
2 |
4 |
|a Immunology.
|
| 650 |
2 |
4 |
|a Geriatrics/Gerontology.
|
| 700 |
1 |
|
|a Fulop, Tamas.
|e editor.
|
| 700 |
1 |
|
|a Franceschi, Claudio.
|e editor.
|
| 700 |
1 |
|
|a Hirokawa, Katsuiki.
|e editor.
|
| 700 |
1 |
|
|a Pawelec, Graham.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|