Inhibitors of Protein Kinases and Protein Phosphates /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Pinna, Lorenzo A. (Editor ), Cohen, Patricia T.W. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2005.
Edición:1st ed. 2005.
Colección:Handbook of Experimental Pharmacology, 167
Materias:
Tabla de Contenidos:
  • Protein Kinase Inhibitors for the Treatment of Disease: The Promise and the Problems
  • General Aspects of PKs Inhibition
  • New Design Strategies for Ligands That Target Protein Kinase-Mediated Protein-Protein Interactions
  • Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases
  • The Paullones: A Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3
  • Pharmacological Potential of p38 MAPK Inhibitors
  • Inhibitors of PKA and Related Protein Kinases
  • Inhibitors of Protein Kinase CK2: Structural Aspects
  • Aminoglycoside Kinases and Antibiotic Resistance
  • Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases
  • Protein Tyrosine Phosphatases as Therapeutic Targets
  • Structure-Based Design of Protein Tyrosine Phosphatase Inhibitors
  • Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target
  • Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity
  • Inhibitors in Clinical Use or Advanced Clinical Trials
  • Clinical Immunosuppression using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus
  • Targeted Therapy with Imatinib: An Exception or a Rule?
  • Clinical Aspects of Imatinib Therapy
  • Isoquinolinesulfonamide: A Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy
  • Discovery and Development of Iressa: The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase.