Hedgehog signaling activation in human cancer and its clinical implications /
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| Format: | eBook |
| Language: | English |
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New York, NY :
Springer New York : Imprint: Springer,
2011.
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| Edition: | 1st ed. 2011. |
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Table of Contents:
- Overview of hedgehog signaling pathway
- Regulation of Hh morphogene gradient
- Smoothened Signaling through a G-protein Effector Network.- Kinases and phosphatases in hedgehog signaling
- Signaling Cross-talk of Oncogenic KRAS and Hedgehog Pathways in Pancreatic Cancer.- Crosstalks between PKC and hedgehog signaling.- Activation of Hh signaling in human cancer.- Hedgehog signaling in pediatric brain tumors
- Hedgehog Signaling in Mammary Gland Development and Breast Cancer
- Hedgehog signaling and cancer therapeutic resistance.- Small-molecule Inhibitors of the Hedgehog Pathway.- Cyclopamine and its derivatives for cancer therapeutics.-.