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140726s2014 xxu| s |||| 0|eng d |
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|a 9781493912155
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| 024 |
7 |
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|a 10.1007/978-1-4939-1215-5
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Mouse Genetics :
|b Methods and Protocols /
|c edited by Shree Ram Singh, Vincenzo Coppola.
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| 250 |
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|a 1st ed. 2014.
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| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2014.
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| 300 |
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|a XIV, 475 p. 92 illus., 68 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1194
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| 505 |
0 |
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|a Development of Pronuclear Injection-Based Targeted Transgenesis in Mice Through Cre–loxP Site-Specific Recombination -- Generation of Conditional Knockout Mice -- Generating Mouse Lines for Lineage Tracing and Knockout Studies -- Generation of an Allelic Series of Knock-In Mice Using Recombinase-Mediated Cassette Exchange (RMCE) -- Generating Chimeric Mice from Embryonic Stem Cells via Vial Coculturing or Hypertonic Microinjection -- Genetic Inducible Fate Mapping in Adult Mice Using Tamoxifen-Dependent Cre Recombinases -- Intra cytoplasmic Sperm Injection (ICSI)-Mediated Transgenesis in Mice -- Generation of Bacterial Artificial Chromosome (BAC) Transgenic Mice -- Generation of Genetically Engineered Mice by the piggyBac Transposon System -- Generation and Applications of MADM-Based Mouse Genetic Mosaic System -- Generation of Mouse Lines Conditionally Over-Expressing MicroRNA Using the Rosa26-Lox-Stop-Lox System -- In Situ Hybridization (Both Radioactive and Non-Radioactive) and Spatiotemporal Gene Expression Analysis -- Isolation and Handling of Mouse Embryonic Fibroblasts -- Generation of Induced Pluripotent Stem Cells from Mouse Adipose Tissue -- Pdx1 (GFP/w) Mice for Isolation, Characterization and Differentiation of Pancreatic Progenitor Cells -- Generation of Transgenic Mouse Fluorescent Reporter Lines for Studying Hematopoietic Development -- Analyzing Gene Function in Adult Long-Term Hematopoietic Stem Cells Using the Interferon Inducible Mx1-Cre Mouse System -- Generation of Transgenic Mice by Exploiting Spermatogonial Stem Cells In Vivo -- Methods for the Detection of Genome Instability Derived from Replication Stress in Primary Mouse Embryonic Fibroblasts -- Transgenic Nude Mice Ubiquitously-Expressing Fluorescent Proteins for Color-Coded Imaging of the Tumor Microenvironment -- Genetically Engineered Insertional Mutagenesis in Mice to Model Cancer: Sleeping Beauty -- Generating Double Knockout Mice to Model Genetic Intervention for Diabetic Cardiomyopathy in Humans -- Experimental Osteoarthritis Models in Mice -- Mouse Models and Methods for Studying Human Disease, Acute Kidney Injury (AKI) -- Mouse Models of Acute and Chronic Colitis -- Manipulation and Assessment of Gut Microbiome for Metabolic Studies.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
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0 |
|a Animal genetics.
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| 650 |
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0 |
|a Animal models in research.
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| 650 |
1 |
4 |
|a Human Genetics.
|
| 650 |
2 |
4 |
|a Animal Genetics and Genomics.
|
| 650 |
2 |
4 |
|a Animal Models.
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| 700 |
1 |
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|a Singh, Shree Ram.
|e editor.
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| 700 |
1 |
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|a Coppola, Vincenzo.
|e editor.
|
| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|