Hypoxia and Cancer : Biological Implications and Therapeutic Opportunities /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Melillo, Giovanni. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2014.
Edición:1st ed. 2014.
Colección:Cancer Drug Discovery and Development,
Materias:
Tabla de Contenidos:
  • Preface
  • Hypoxia and breast cancer metastasis
  • Hypoxia and the DNA damage response
  • Hypoxia and non-coding RNAs
  • Hypoxia and ROS
  • Hypoxia and gene expression
  • Carbonic anhydrase IX: from biology to therapy
  • Imaging the hypoxic tumor microenvironment in preclinical models
  • Clinical imaging of hypoxia
  • Hypoxia, antiangiogenic therapy and metastasis
  • UPR and therapeutic opportunities
  • Targeting the hypoxic phenotype
  • Marianne Nordsmark: Hypoxia and Radiation therapy
  • Pharmacological strategies targeting hypoxia
  • Targeting the hypoxic tumor microenvironment
  • Clinical exploitation of hypoxia
  • Index.