High Throughput Screening : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Janzen, William P. (Editor ), Bernasconi, Paul. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2009.
Edición:2nd ed. 2009.
Colección:Methods in Molecular Biology, 565
Materias:
Tabla de Contenidos:
  • Design and Implementation of High-Throughput Screening Assays
  • Creation of a Small High-Throughput Screening Facility
  • Informatics in Compound Library Management
  • Statistics and Decision Making in High-Throughput Screening
  • Enzyme Assay Design for High-Throughput Screening
  • Application of Fluorescence Polarization in HTS Assays
  • Screening G Protein-Coupled Receptors: Measurement of Intracellular Calcium Using the Fluorometric Imaging Plate Reader
  • High-Throughput Automated Confocal Microscopy Imaging Screen of a Kinase-Focused Library to Identify p38 Mitogen-Activated Protein Kinase Inhibitors Using the GE InCell 3000 Analyzer
  • Recent Advances in Electrophysiology-Based Screening Technology and the Impact upon Ion Channel Discovery Research
  • Automated Patch Clamping Using the QPatch
  • High-Throughput Screening of the Cyclic AMP-Dependent Protein Kinase (PKA) Using the Caliper Microfluidic Platform
  • Use of Primary Human Cells in High-Throughput Screens.