MACPF/CDC Proteins - Agents of Defence, Attack and Invasion /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Anderluh, Gregor. (Editor ), Gilbert, Robert. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Subcellular Biochemistry, 80
Materias:
Tabla de Contenidos:
  • Part I: Overview of MACPF/CDCs
  • Introduction: Brief Historical Overview
  • Distribution of MACPF/CDC proteins
  • Evolution of the Complement System
  • Part II: Structures of MACPF/CDCs
  • Structural Features of Cholesterol Dependent Cytolysins and Comparison to other MACPF-domain containing proteins
  • Perfringolysin O Structure and Mechanism of Pore Formation as a Paradigm for Cholesterol-Dependent Cytolysins
  • Structural Biology of the Membrane Attack Complex
  • Part III: Functional aspect
  •  Membrane Interactions and Cellular Effects of MACPF/CDC Proteins
  • The Biology of Pneumolysin
  • Multifaceted Activity of Listeriolysin O, the Cholesterol-Dependent Cytolysin of Listeria monocytogenes
  • Perforin - a Key Pore-Forming Protein for Immune Control of Viruses and Cancer
  • Perforin and Human Diseases
  • The role of MACPF Proteins in the Biology of Malaria and other Apicomplexan Parasites
  • Chlamydial MACPF Protein CT153
  • Fungal MACPF-Like Proteins and Aegerolysins: Bi-Component Pore-Forming Proteins?
  • Fluorescence Imaging of MACPF/CDC Proteins: New Techniques and Their Application.