Next Generation Sequencing in Cancer Research : Volume 1: Decoding the Cancer Genome /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Wu, Wei. (Editor ), Choudhry, Hani. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Materias:
Tabla de Contenidos:
  • Introduction: next generation sequencing technology and cancer research
  • The majority of total nuclear-encoded non-ribosomal RNA in a human cell is ‘dark matter’ unannotated RNA
  • Total RNA-seq of breast cancer in hypoxia
  • Altered antisense-to-sense transcript ratios in breast cancer
  • Identification of piRNAs in Hela cells by massive parallel sequencing
  • Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia
  • Whole-Exome Sequencing Identifies FAM20A Mutations as a Cause of Amelogenesis Imperfecta and Gingival Hyperplasia Syndrome
  • Whole-exome sequencing in CIC and IDH1/2 contributing to human oligodendroglioma
  • Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing
  • Tumour evolution inferred by single-cell sequencing
  • Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq
  • Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNASeq analysis
  • Whole genome DNA methylation analysis based on high throughput sequencing technology
  • Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors
  • High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
  • MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action
  • Genome-wide identification of polycomb-associated RNAs by RIP-seq
  • Single-molecule sequencing: sequence methods to enable accurate quantisation
  • Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells
  • Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
  • The genome information process for cancer research: the challenge and perspective
  • Index.