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02950nam a22003135i 4500 |
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20201008132137.0 |
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cr nn 008mamaa |
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190423s2019 xxu| s |||| 0|eng d |
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|a 9781493992164
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| 024 |
7 |
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|a 10.1007/978-1-4939-9216-4
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Non-Natural Nucleic Acids :
|b Methods and Protocols /
|c edited by Nathaniel Shank.
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| 250 |
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|a 1st ed. 2019.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2019.
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| 300 |
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|a XI, 315 p. 95 illus., 41 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 1973
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| 505 |
0 |
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|a Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs -- Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites, 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 2'-Deoxycytidine -- Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue -- Synthesis of Base-Modified dNTPs through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA -- 2ʹ-C,4ʹ-C-Ethyleneoxy-Bridged 2ʹ-Deoxyribonucleic Acids (EoDNAs) with Thymine Nucleobases: Synthesis, Duplex-Forming Ability, and Enzymatic Stability -- Synthesis Protocols for Simple Uncharged Glycol Carbamate Nucleic Acids -- Synthesis of Nucleobase-Functionalized Morpholino Monomers -- Synthesis and Application of LKγT Peptide Nucleic Acids -- Aminoglycoside Functionalization as a Tool for Targeting Nucleic Acids -- Preparation and Purification of Oligodeoxynucleotide Duplexes Containing a Site-Specific, Reduced, Chemically-Stable Covalent Interstrand Cross-Link between a Guanine Residue and an Abasic Site -- Copper-Catalyzed Alkyne-Azide Cycloaddition on the Solid Phase for the Preparation of Fully Click-Modified Nucleic Acids -- Labeling Peptide Nucleic Acids with Indium-111 -- Site-Specific Labeling of DNA via PCR with an Expanded Genetic Alphabet -- Flexible Nucleic Acids (FNAs) As Informational Molecules: Enzymatic Polymerization of fNTPs on DNA Templates and Nonenzymatic Oligomerization of RNA on FNA Templates -- Artificial Nucleosides as Diagnostic Probes to Measure Translesion DNA Synthesis -- FRET Assay for Ligands Targeting the Bacterial A-Site RNA -- The Use of Serinol Nucleic Acids as Ultrasensitive Molecular Beacons -- Oligonucleotide Primers with G8AE-Clamp Modifications for RT-qPCR Detection of the Low-Copy dsRNA -- Determining Steady-State Kinetics of DNA Polymerase Nucleotide Incorporation.
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| 650 |
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|a Nucleic acids.
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| 650 |
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0 |
|a Genetics.
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| 650 |
1 |
4 |
|a Nucleic Acid Chemistry.
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| 650 |
2 |
4 |
|a Genetics and Genomics.
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| 700 |
1 |
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|a Shank, Nathaniel.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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