Proteomics for Biomarker Discovery : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Brun, Virginie. (Editor ), Couté, Yohann. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2019.
Edición:1st ed. 2019.
Colección:Methods in Molecular Biology, 1959
Materias:
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024 7 |a 10.1007/978-1-4939-9164-8  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 0 |a Proteomics for Biomarker Discovery :  |b Methods and Protocols /  |c edited by Virginie Brun, Yohann Couté. 
250 |a 1st ed. 2019. 
260 # # |a New York, NY :  |b Springer New York :  |b Imprint: Humana,  |c 2019. 
300 |a XII, 292 p. 52 illus., 47 illus. in color. :  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in Molecular Biology,  |v 1959 
505 0 |a Pre- and Post-Analytical Factors in Biomarker Discovery -- Pre-Fractionation of Non-Circulating Biological Fluids to Improve Discovery of Clinically Relevant Protein Biomarkers -- Serum Exosome Isolation by Size-Exclusion Chromatography for the Discovery and Validation of Preeclampsia-Associated Biomarkers -- Protein Biomarker Discovery Using Human Blood Plasma Microparticles -- A Standardized and Reproducible Proteomics Protocol for Bottom-Up Quantitative Analysis of Protein Samples Using SP3 and Mass Spectrometry -- Analyzing Cerebrospinal Fluid Proteomes to Characterize Central Nervous System Disorders: A Highly Automated Mass Spectrometry-Based Pipeline for Biomarker Discovery -- Lys-C/Trypsin Tandem-Digestion Protocol for Gel-Free Proteomic Analysis of Colon Biopsies -- Tube-Gel: A Fast and Effective Sample Preparation Method for High-Throughput Quantitative Proteomics -- Protein Biomarker Discovery in Non-Depleted Serum by Spectral Library-Based Data-Independent Acquisition Mass Spectrometry -- Discovering Protein Biomarkers from Clinical Peripheral Blood Mononuclear Cells Using Data-Independent Acquisition Mass Spectrometry -- Intact Protein Analysis by LC-MS for Characterizing Biomarkers in Cerebrospinal Fluid -- Detection of Proteoforms Using Top-Down Mass Spectrometry and Diagnostic Ions -- Development of a Highly Multiplexed SRM Assay for Biomarker Discovery in Formalin-Fixed Paraffin-Embedded Tissues -- Development and Validation of Multiple Reaction Monitoring (MRM) Assays for Clinical Applications -- Protein-Level Statistical Analysis of Quantitative Label-Free Proteomics Data with ProStaR -- Computation and Selection of Optimal Biomarker Combinations by Integrative ROC Analysis using CombiROC -- PanelomiX for the Combination of Biomarkers -- Designing an In Silico Strategy to Select Tissue-Leakage Biomarkers Using the Galaxy Framework. 
650 0 |a Proteomics. 
650 0 |a Proteins . 
650 1 4 |a Proteomics. 
650 2 4 |a Protein Science. 
700 1 |a Brun, Virginie.  |e editor. 
700 1 |a Couté, Yohann.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
900 |a Libro descargado a ALEPH en bloque (proveniente de proveedor)