Nuclear Receptors: From Structure to the Clinic /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: McEwan, Iain J. (Editor ), Kumar, Raj. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Materias:
Tabla de Contenidos:
  • 1. Twenty-five Years of Nuclear Receptor Structure Analysis: From the Laboratory to the Clinic
  • Part A. ALLOSTERIC REGULATION AND NUCLEAR RECEPTOR COMPLEX DYNAMICS. -2. Corticosteroid Receptors
  • 3. Glucocorticoid Receptor Structure and Function
  • 4. What Determines the Difference in DNA Binding Between the Androgen and the Glucocorticoid Receptors?
  • 5. Allosteric Regulation and Intrinsic Disorder in Nuclear Hormone Receptors
  • 6. Structural Analyses of Ordered and Disordered Regions in Ecdysteroid Receptor
  • 7. Structural Analysis of Heterodimeric Nuclear Receptors
  • Part B. NUCLEAR RECEPTOR CO-REGULATORY PROTEIN INTERACTIONS
  • 8. Primate-specific Multi-functional Androgen Receptor Coregulator and Proto-oncogene Melanoma Antigen-A11 (MAGE-A11)
  • 9. Assembly and Regulation of Nuclear Receptor Corepressor Complexes
  • Part C. TAKING NUCLEAR RECEPTOR STRUCTURE INTO THE CLINIC
  • 10. Thinking Outside the Box: Alternative Binding Sites in the Ligand Binding Domain of Nuclear Receptors
  • 11. Selective Estrogen Receptor Modulators (SERMs) and Selective Androgen Receptor Modulators (SARMs).