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151217s2016 gw | s |||| 0|eng d |
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|a 9783319237930
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024 |
7 |
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|a 10.1007/978-3-319-23793-0
|2 doi
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040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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245 |
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|a Organic Cation Transporters :
|b Integration of Physiology, Pathology, and Pharmacology /
|c edited by Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter.
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250 |
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|a 1st ed. 2016.
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260 |
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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300 |
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|a XV, 264 p. 34 illus., 14 illus. in color. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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337 |
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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|a Introduction to the cellular transport of organic cations -- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism -- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity -- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy -- Physiological and pathological regulation of transporters for organic cations -- Endocrine and metabolic regulation of transporters for organic cations -- Organic cation transporters (OCTs) as modulators of behavior and mood -- Organic cation transporters as modulators of neurodegeneration and neuroprotection -- Translational relevance of animal models for the study of organic cation transporter function -- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.
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650 |
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|a Human physiology.
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650 |
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|a Pharmacology.
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650 |
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|a Pathology.
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650 |
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4 |
|a Human Physiology.
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650 |
2 |
4 |
|a Pharmacology/Toxicology.
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650 |
2 |
4 |
|a Pathology.
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700 |
1 |
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|a Ciarimboli, Giuliano.
|e editor.
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700 |
1 |
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|a Gautron, Sophie.
|e editor.
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700 |
1 |
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|a Schlatter, Eberhard.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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