Proteomic Methods in Neuropsychiatric Research /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2017.
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| Edición: | 1st ed. 2017. |
| Colección: | Proteomics, Metabolomics, Interactomics and Systems Biology ;
974 |
| Materias: |
Tabla de Contenidos:
- Preface – Proteomic studies in psychiatric disease and neurological disorders
- Part 1: REVIEWS
- Application of proteomic techniques for improved stratification and treatment of schizophrenia patients
- Multiplexing biomarker methods, proteomics and considerations for Alzheimer’s disease
- What have proteomic studies taught us about novel drug targets in autism?
- Application of proteomic approaches to accelerate drug development for psychiatric disorders
- Proteomic biomarker identification in cerebrospinal fluid for leptomeningeal metastases with neurological complications
- Connecting brain proteomics with behavioural neuroscience in translational animal models of neuropsychiatric disorders
- LC-MSE for qualitative and quantitative proteomicstudies of psychiatric disorders
- The utility of multiplex assays for identification of proteomic signatures in psychiatry
- Part 2: PROTOCOLS
- Blood sampling and preparation procedures for proteomic biomarker studies of psychiatric disorders
- Multiplex immunoassay profiling of serum in psychiatric disorders
- Sequential immunopreciptation of secretory vesicle proteins from biosynthetically-labelled cells
- 2d gel electrophoresis of insulin secretory granule proteins from biosynthetically-labelled pancreatic islets
- Two-dimensional gel electrophoresis: a reference protocol
- A two-dimensional difference gel electrophoresis (2D-DIGE) protocol for studies of neural precursor cells
- Identifying biomarker candidates in the blood plasma or serum proteome
- Selective reaction monitoring mass spectrometry for quantitation of glycolytic enzymes in post-mortem brain samples
- A selected reaction monitoring mass spectrometry protocol for validation of proteomic biomarker candidates in studies of psychiatric disorders
- Application of iTRAQ shotgun proteomics for measurement of brain proteins in studies of psychiatric disorders
- Co-immunoprecipitation for deciphering protein interactomes
- Sequential co-immunopreciptation and immunoblot approach to determine oligomerisation of G-protein coupled receptors
- A protocol for producing the maternal low protein rat model: a tool for pre-clinical proteomic studies
- A clinical study protocol to identify serum biomarkers predictive of response to antipsychotics in schizophrenia patients
- Generation of the acute phencyclidine rat model for proteomic studies of schizophrenia A protocol for generation of a corticosterone model of psychiatric disorders
- MK-801-treated oligodendrocytes as a cellular model to study schizophrenia
- Combining patient-reprogrammed neural cells and proteomics as a model to study psychiatric disorders
- SILAC mass spectrometry profiling: a psychiatric disorder perspective
- Preparation of peripheral blood mononuclear cells (PBMCs) as a model for proteomic studies psychiatric disorders
- Proteomic profiling of skin fibroblasts as a model of schizophrenia Proteomic profiling of the pituitary gland in studies of psychiatric disorders
- Development of an assay for measuring proprotein-conversion activity on a multiplex magnetic bead-based array platform
- Phenotyping multiple subsets of immune cells in situ in formalin-fixed, paraffin-embedded tissue sections
- Lab-on-a-chip proteomic assays for psychiatric disorders
- Development of a user-friendly app for testing blood coagulation status in schizophrenia patients
- Part 3:FUTURE PERSPECTIVES
- Proteomic approaches to enable point-of-care testing and personalized medicine for psychiatric disorders.