RNA Interference : Challenges and Therapeutic Opportunities /
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY :
Springer New York : Imprint: Humana,
2015.
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| Edition: | 1st ed. 2015. |
| Series: | Methods in Molecular Biology,
1218 |
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Table of Contents:
- RNA Interference: Mechanisms, Technical Challenges and Therapeutic Opportunities
- Nanostructured RNAs for RNA Interference
- One Long Oligonucleotide or Two Short Oligonucleotides Based shRNA Construction and Expression
- PLGA Microspheres Encapsulating siRNA
- Magnetic Nanoparticle and Magnetic Field Assisted siRNA Delivery In Vitro
- Cytoplasmic Delivery of siRNAs to Monocytes and Dendritic Cells Via Electroporation
- Delivery of siRNAs to Cancer Cells Via Bacteria
- Microwell Array-Mediated Delivery of Lipoplexes Containing Nucleic Acids for Enhanced Therapeutic Efficacy
- Modulating the Tumor Microenvironment with RNA Interference as a Cancer Treatment Strategy
- Targeted In Vivo Delivery of siRNA and an Endosome-Releasing Agent to Hepatocytes
- Cell-Internalization SELEX: Method for Identifying Cell-Internalizing RNA Aptamers for Delivering siRNAs to Target Cells
- Strategies for siRNA Navigation to Desired Cells
- Analysis of RNA Interference-Mediated Hepatic Gene Silencing Following Murine Hydrodynamic Injection of Guanidinopropyl-Modified siRNAs
- Therapy of Respiratory Viral Infections with Intranasal siRNAs
- Engineering Therapeutic Cancer Vaccines that Activate Anti-Tumor Immunity
- Immunosuppressive Factor Blockade in Dendritic Cells Via siRNAs Results in Objective Clinical Responses
- Targeting bcr-abl Transcripts with siRNAs in an Imatinib-Resistant Chronic Myeloid Leukemia Patient: Challenges and Future Directions
- A Facile Method for Interfering with Off-Target Silencing Mediated by the Sense Strand
- Overcoming the Challenges of siRNA Activation of Innate Immunity: Design Better Therapeutic siRNAs
- Gene Silencing In Vitro and In Vivo Using Intronic MicroRNAs
- In Silico Identification of Novel Endo-siRNAs
- Computer-Assisted Annotation of Small RNA Transcriptomes
- miR-CATCH: MicroRNA Capture Affinity Technology
- Roles of MicroRNAs in Cancers and Development
- Targeting MicroRNAs to Withstand Cancer Metastasis
- Urinary MicroRNAs as a New Class of Non-Invasive Biomarkers in Oncology, Nephrology and Cardiology
- Magnetic Bead-Based Isolation of Exosomes
- Modified 2'-Ribose Small RNAs Function as Toll-Like Receptor-7/8 Antagonists.