Protein Kinase CK2 Cellular Function in Normal and Disease States /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Ahmed, Khalil. (Editor ), Issinger, Olaf-Georg. (Editor ), Szyszka, Ryszard. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Advances in Biochemistry in Health and Disease ; 12
Materias:
Tabla de Contenidos:
  • 1. CK2 Suppression of Apoptosis
  • 2. Structural Determinants of CK2 Regulation
  • 3. Targeting Protein Kinase: CK2 Suppresses Pro-Survival Signaling Pathways and Growth of Gliobastoma
  • 4. The Roles of CK2 in Drosophila Neurogenesis
  • 5. Targeting the CK2 Subunit Interface: Challenge and Usefulness
  • 6. CK2 in Wnt/β-catenin signaling and embryo development
  • 7. Defective expression of CK2β promotes EMT and stemness properties both required for breast cancer progression
  • 8. Chemical Biology Approaches to Identify CK2 Substrates and Perform Unbiased Evaluation of CK2 Inhibitors
  • 9. Development of Screening Systems and Identification of Novel Potent Inhibitors of Human Protein Kinase CK2
  • 10. Protein Kinase CK2: At the Crossroad of Regulatory Cellular Pathways
  • 11. Functional Regulation of DYRK Family Protein Kinases by Cellular Binding Partners
  • 12. Regulation of CK2 in pancreatic β cells
  • 13. Recent impressions from the configurational and conformational space captured by protein kinase CK2
  • 14. Role of CK2 in Plant Responses to Abiotic Stress
  • 15. “Genuine” Casein Kinase: The False Sister of CK2: Phosphorylates-Secreted Proteins
  • 16. CK2: – A Novel Player in L-DOPA induced dyskinesia in a mouse model of Parkinson’s disease
  • 17. CK2 function in the regulation of Akt Pathway: new findings and perspectives
  • 18. CK2 structure from yeast to human
  • 19. Cellular zinc signaling is triggered by CK2
  • 20. A Nanomedicine Approach to Targeting CK2 for Cancer therapy
  • 21. Bisubstrate approach for construction of high-affinity inhibitors and optical probes for protein kinase CK2.