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141118s2015 xxu| s |||| 0|eng d |
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|a 9781493920747
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|a 10.1007/978-1-4939-2074-7
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Protocols in In Vitro Hepatocyte Research /
|c edited by Mathieu Vinken, Vera Rogiers.
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| 250 |
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|a 1st ed. 2015.
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2015.
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| 300 |
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|a XVI, 406 p. 72 illus., 26 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Methods in Molecular Biology,
|v 1250
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|a Isolation And Culture Of Mouse Hepatocytes: Gender-Specific Gene Expression Responses To Chemical Treatments -- Cryopreservation of Hepatocytes -- Culture Conditions Promoting Hepatocyte Proliferation And Cell Cycle Synchronization -- Immortalized Human Hepatic Cell Lines For In Vitro Testing And Research Purposes -- Culture and Functional Characterization Of Human Hepatoma Hepg2 Cells -- Establishment And Characterization Of An In Vitro Model Of Fas-Mediated Hepatocyte Cell Death -- Serum-Free Directed Differentiation Of Human Embryonic Stem Cells To Hepatocytes -- Human Skin-Derived Precursor Cells: Isolation, Expansion And Hepatic Differentiation -- Generation Of Hepatocytes From Pluripotent Stem Cells For Drug Screening and Developmental Modeling -- Differentiation-Promoting Medium Additives For Hepatocyte Cultivation and Cryopreservation -- Co-Culture and Long-Term Maintenance Of Hepatocytes -- Primary Hepatocytes In Sandwich Culture -- Establishing Liver Bioreactors For In Vitro Research -- Epigenetic Modifications As Anti-Dedifferentiation Strategy For Primary Hepatocytes In Culture -- Transfection Of Primary Hepatocytes With Liver-Enriched Transcription Factors Using Adenoviral Vectors -- Transcriptomics Of Hepatocytes Treated With Toxicants For Investigating Molecular Mechanisms Underlying Hepatotoxicity -- Global Microrna Analysis In Primary Hepatocyte Cultures -- Mass Spectrometry-Based Proteomics For Relative Protein Quantification And Biomarker Identification In Primary Human Hepatocytes -- Targeted Metabolomics For Homocysteine-Related Metabolites In Primary Hepatocytes -- Measurement Of Cytochrome P450 Enzyme Induction And Inhibition In Human Hepatoma Cells -- Analysis Of Sinusoidal Drug Uptake Transporter Activities In Primary Human Hepatocytes -- Measurement Of Albumin Secretion As Functionality Test In Primary Hepatocyte Cultures -- Measurement Of Blood Coagulation Factor Synthesis In Cultures Of Human Hepatocytes -- Functionality Testing Of Primary Hepatocytes In Culture By Measuring Urea Synthesis -- Assay Of Bile Acid Conjugation And Excretion In Human Hepatocytes -- General Cytotoxicity Assessment By Means Of The MTT Assay -- Measurement Of Apoptotic And Necrotic Cell Death In Primary Hepatocyte Cultures -- Critical Factors In The Assessment Of Cholestatic Liver Injury in vitro -- In vitro Cell Culture Models Of Hepatic Steatosis -- Assessment Of Liver Fibrotic Insults in vitro. .
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|a Pharmacology.
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| 650 |
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|a Pharmacology/Toxicology.
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| 700 |
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|a Vinken, Mathieu.
|e editor.
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| 700 |
1 |
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|a Rogiers, Vera.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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