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170429s2017 gw | s |||| 0|eng d |
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|a 9783319526737
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| 024 |
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|a 10.1007/978-3-319-52673-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Non-canonical Cyclic Nucleotides /
|c edited by Roland Seifert.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2017.
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| 300 |
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|a VIII, 387 p. 65 illus., 35 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Handbook of Experimental Pharmacology,
|v 238
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| 505 |
0 |
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|a Part I: 3’,5’-cCMP and 3’,5’-cUMP as second messengers: cCMP and cUMP across the tree of life: From cCMP and cUMP generators to cCMP- and cUMP-regulated cell functions -- cCMP and cUMP in apoptosis: Concepts and methods -- Mammalian nucleotidyl cyclases and their nucleotide binding sites -- The Pseudomonas aeruginosa exoenzyme Y: A promiscuous nucleotidyl cyclase edema factor and virulence determinant -- Cyclic nucleotide monophosphates in plants and plant signalling -- cAMP-dependent protein kinase and cGMP-dependent protein kinase as cyclic nucleotide effectors -- Regulation of HCN ion channels by non-canonical cyclic nucleotides -- Identification of cCMP and cUMP substrate proteins and cross-talk between cNMPs -- Inactivation of non-canonical cyclic nucleotides: Hydrolysis and transport -- Part II: 3’,5’-cIMP, 8-nitro-cGMP, 2’,3’-cNMPs and cyclic dinucleotides as signaling molecules: 3’,5’-cIMP as potential second messenger in the vascular wall -- The discovery of 2’,3’-cNMPs in mammalian systems: From rodents to humans -- 8-Nitro-cGMP: A novel protein-reactive cNMP and its emerging roles in autophagy -- Cyclic dinucleotides in the scope of the mammalian immune system -- Part III: Methods/Tools for cNMP research: Mass-spectrometric analysis of non-canonical cyclic nucleotides -- Medicinal chemistry of the noncanonical cyclic nucleotides cCMP and cUMP -- Holistic methods for the analysis of cNMP effects -- The chemistry of the non-canonical cyclic dinucleotide 2'3'-cGAMP and its analogs.
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| 650 |
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|a Pharmacology.
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| 650 |
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|a Biochemistry.
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| 650 |
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|a Human physiology.
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| 650 |
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4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Biochemistry, general.
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| 650 |
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4 |
|a Human Physiology.
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| 700 |
1 |
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|a Seifert, Roland.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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