Ras Superfamily Small G Proteins: Biology and Mechanisms 1 : General Features, Signaling /
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| Format: | eBook |
| Language: | English |
| Published: |
Vienna :
Springer Vienna : Imprint: Springer,
2014.
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| Edition: | 1st ed. 2014. |
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Table of Contents:
- Evolution of the Ras Superfamily of GTPases
- The structure of the G domain of the Ras superfamily
- GEFs and GAPs: Mechanisms and Structures
- Bacterial protein toxins acting on small GTPases
- Posttranslational modifications of small G proteins
- Targeting the Raf-MEK-ERK Mitogen-Activates Protein Kinase Cascade for the Treatment of RAS Mutant Cancers
- RAS Genes and Cancer
- The Spatial Organization of Ras Signaling
- Ras Nanoclusters
- Mouse Models of Ras induced Tumors and Developmental Disorders
- Rap signaling
- The coordinated biology and signaling partners of Ral G-proteins
- Structure and Function of the mTOR Activator Rheb
- Classical Rho proteins: Biochemistry of molecular switch function and regulation
- Atypical Rho family members
- Molecular Structures, Cellular Functions and Physiological Roles of Rho Effectors
- Principles driving the spatial organization of Rho GTPase signaling at synapses
- Rho GTPases in Cancer.