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02960nam a22003735i 4500 |
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000290281 |
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20210907143839.0 |
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cr nn 008mamaa |
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170602s2017 gw | s |||| 0|eng d |
| 020 |
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|a 9783319540641
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| 024 |
7 |
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|a 10.1007/978-3-319-54064-1
|2 doi
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| 040 |
|
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 100 |
1 |
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|a Bleidorn, Christoph.
|e author.
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| 245 |
1 |
0 |
|a Phylogenomics :
|b An Introduction /
|c by Christoph Bleidorn.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
# |
|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2017.
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| 300 |
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|a XIII, 222 p. 89 illus., 87 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a 1. Genomes -- 01.1 Prokaryotes vs. Eukaryotes -- 01.2 Genome Structure -- 01.3 Genome Sizes -- 01.4 Human Genome and Ancient DNA (Neandertaler, Denisova) -- 2. Genomes of Organelles -- 02.1 Mitochondria -- 02.2 Plastids -- 02.3 Outlook Obligate Endosymbionts -- 3. Transcriptomes -- 03.1 mRNA -- 03.2 Transcripts -- 03.3 Expression Level -- 03.4 Alternative Splicing -- 4. Sequencing Techniques -- 04.1 Sanger -- 04.2 Illumina -- 04.3 454 -- 04.4 PacBio -- 04.5 Outlook Nanopore Sequencing -- 5. Genome Sequencing Strategies -- 05.1 Whole Genome Shotgun -- 05.2 RADseq -- 05.3 Target Enrichment -- 05.4 RNAseq -- 6. Assembly and Mapping -- 06.1 Assembling Strategies (kmer vs OLC) -- 06.2 Data Quality and Filtering -- 06.3 Re-Sequencing and Mapping -- 06.4 De novo Assembly Genome -- 06.5 De novo Assembly Transcriptome -- 7. Locating Genes -- 07.1 Orthology vs. Paralogy -- 07.2 BLAST and Successors -- 07.3 Hidden Markov Profile -- 07.4 Ortholog Conjecture -- 8. Alignment -- 08.1 Alignment Strategies -- 08.2 Alignment Masking -- 9. Phylogenetic Analysis -- 09.1 Distance Measurements -- 09.2 Maximum Parsimony -- 09.3 Maximum Likelihood -- 09.4 Bayesian Inference -- 09.5 Supermatrix vs. Single Gene Analysis (Gene Trees vs. Species Trees) -- 10. Systematic Errors in phylogenetic Analysis -- 10.1 Prediction: Evolutionary Models -- 10.2 Heterogenity Nucleotide/Amino Acid-Composition -- 10.3 Variation of substitution rate between the lines -- 10.4 Variation of substitution rate over time -- 10.5 New Approaches to Correct systematic Errors -- 11. Genome-wide Characteristics -- 11.1 Gene Order -- 11.2 Mobile Elements -- 11.3 microRNAs -- 11.4 Differences in the genetic code -- 12. Index -- 13. References.
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| 650 |
|
0 |
|a Evolutionary biology.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
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0 |
|a Bioinformatics.
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| 650 |
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0 |
|a Microbial genetics.
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| 650 |
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0 |
|a Microbial genomics.
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| 650 |
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0 |
|a Animal genetics.
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| 650 |
1 |
4 |
|a Evolutionary Biology.
|
| 650 |
2 |
4 |
|a Human Genetics.
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| 650 |
2 |
4 |
|a Bioinformatics.
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| 650 |
2 |
4 |
|a Microbial Genetics and Genomics.
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| 650 |
2 |
4 |
|a Animal Genetics and Genomics.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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