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03944nam a22003615i 4500 |
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20211005081252.0 |
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cr nn 008mamaa |
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161013s2016 gw | s |||| 0|eng d |
| 020 |
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|a 9783319307053
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| 024 |
7 |
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|a 10.1007/978-3-319-30705-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Redox-Active Therapeutics /
|c edited by Ines Batinić-Haberle, Júlio S. Rebouças, Ivan Spasojević.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
# |
# |
|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a XXX, 694 p. 162 illus., 124 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Oxidative Stress in Applied Basic Research and Clinical Practice,
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| 505 |
0 |
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|a Part 1. Pathophysiological Roles of Superoxide Dismutases (SOD) -- Superoxide and the Superoxide Dismutases: An Introduction by Irwin Fridovich -- The Discovery of Superoxide Dismutase and Its Role in Redox Biology -- Manganese Superoxide Dismutase (MnSOD) and It's Importance in Mitochondrial Function and Cancer -- Regulation of the Cellular Redox Environment by Superoxide Dismutases, Catalase and Glutathione Peroxidases During Tumor Metastasis -- Superoxide Dismutase Family of Enzymes in Brain Neurogenesis and Radioprotection -- Metabolic Production of H2O2 in Carcinogenesis and Cancer Treatment -- Part 2. Redox-Active Therapeutics - Design and Mechanisms of Action -- Mimicking SOD, Why and How: Bio-Inspired Manganese Complexes as SOD Mimics -- Mn Porphyrin-Based Redox-Active Therapeutics -- Cytochrome P450-like Biomimetic Oxidation Catalysts Based on Mn porphyrins as Redox Modulators -- Nitrones as Potent Anticancer Therapeutics -- Salen Manganese Complexes Mitigate Radiation Injury in Normal Tissues Through Modulation of Tissue Environment -- Molecular Basis for Anticancer and Antiparasite Activities of Copper-Based Drugs -- Small Signaling Molecules and CO-Releasing Molecules (CORMs) for the Modulation of the Cellular Redox Metabolism -- HNO/Thiol Biology as a Therapeutic Target -- Part 3. Redox-Active Therapeutics in Cancer -- Advances in Breast Cancer Therapy Using Nitric Oxide and Nitroxyl Donor Agents -- Mechanisms by Which Manganese Porphyrins Affect Signaling in Cancer Cells -- Targeted Therapy for Malignant Brain Tumors -- Redox Therapeutics in Breast Cancer: Role of SOD Mimics -- Anticancer Action of Mn porphyrins in Head and Neck Cancers -- Redox-based Therapeutic Strategies in the Treatment of Skin Cancers -- Role of Oxidative Stress in Erectile Dysfunction after Prostate Cancer Therapy -- Theranostic Nanoconjugates of Tetrapyrrolic Macrocycles and Their Applications in Photodynamic Therapy -- Part 4. Redox-Active Therapeutics in Other Diseases -- Quantum Dots in Photodynamic Therapy -- Metalloporphyrins in CNS injuries -- The Contribution of Nitroxidative Stress to Pathophysiological Pain and Opioid Analgesic Failure -- Amyotrophic Lateral Sclerosis - Present Understanding of the Role of SOD -- Redox Regulation and Misfolding of SOD1: Therapeutic Strategies for Amyotrophic Lateral Sclerosis -- Redox-Based Therapeutics for Prevention, Mitigation, and Treatment of Lung Injury Secondary to Radiation Exposure -- Using Metalloporphyrins to Preserve β Cell Mass and Inhibit Immune Responses in Diabetes -- Redox-Active Metal Complexes in Trypanosomatids.
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| 650 |
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0 |
|a Oxidative stress.
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| 650 |
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0 |
|a Enzymology.
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| 650 |
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0 |
|a Cancer research.
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| 650 |
1 |
4 |
|a Oxidative Stress.
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| 650 |
2 |
4 |
|a Enzymology.
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| 650 |
2 |
4 |
|a Cancer Research.
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| 700 |
1 |
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|a Batinić-Haberle, Ines.
|e editor.
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| 700 |
1 |
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|a Rebouças, Júlio S.
|e editor.
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| 700 |
1 |
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|a Spasojević, Ivan.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
|
| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|