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02011nam a22003135i 4500 |
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000291263 |
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20210915183204.0 |
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cr nn 008mamaa |
| 008 |
170523s2017 gw | s |||| 0|eng d |
| 020 |
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|a 9783319534572
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| 024 |
7 |
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|a 10.1007/978-3-319-53457-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders /
|c edited by Nicola Brunetti-Pierri.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
# |
|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2017.
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| 300 |
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|a IX, 220 p. 32 illus., 19 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Overview: gene transfer strategies, principles, applications -- Manufacturing viral gene therapy vectors: general approaches and challenges -- Retrovirus- and lentivirus-based vectors -- Preclinical and clinical applications of retroviral vectors -- Preclinical and clinical applications of lentiviral vectors -- Retrovirus and lentivirus integration -- Adenovirus-based vectors for gene therapy -- Adenoviral vector-host interactions -- Helper-dependent adenoviral vectors -- Gene therapy for cancer treatment -- Oncolytic adenoviruses for cancer treatment -- Vaccination by gene transfer vectors -- AAV vectors: general features and applications -- Adaptive immune response to viral vector delivery -- Herpes viruses: general features and applications -- RNA interference-based strategy for treatment of human diseases -- Antisense oligonucleotide based therapeutics -- Gene editing strategies -- Nonviral vectors.
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| 650 |
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|a Pharmacology.
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| 650 |
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|a Gene therapy.
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| 650 |
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0 |
|a Molecular biology.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Gene Therapy.
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| 650 |
2 |
4 |
|a Molecular Medicine.
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| 700 |
1 |
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|a Brunetti-Pierri, Nicola.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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