Trinucleotide Repeats : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Richard, Guy-Franck. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2020.
Edición:1st ed. 2020.
Colección:Methods in Molecular Biology, 2056
Materias:
Tabla de Contenidos:
  • Experimenting with Trinucleotide Repeats: Facts and Technical Issues
  • Fast Assays to Detect Interruptions in CTG.CAG Repeat Expansions
  • Tracking Expansions of Stable and Threshold Length Trinucleotide Repeat Tracts In Vivo and In Vitro Using Saccharomyces cerevisiae
  • Quantifying Replication Fork Progression at CTG Repeats by 2D Gel Electrophoresis
  • Genetic Assays to Study Repeat Fragility in Saccharomyces cerevisiae
  • Genetic Screens to Study GAA/TTC and Inverted Repeat Instability in Saccharomyces cerevisiae
  • Monitoring Double-Strand Break Repair of Trinucleotide Repeats Using a Yeast Fluorescent Reporter Assay
  • Analysis of Trinucleotide Repeat Stability by Integration at a Chromosomal Ectopic Site
  • Experimental System to Study Instability of (CGG)n Repeats in Cultured Mammalian Cells
  • Assessing Triplet Repeat Expansions in Human SVG-A Cell Culture
  • The Isolation and Analysis of the CGG-Repeat Size in Male and Female Gametes from a Fragile X Mouse Model
  • In Vitro Synthesis and RNA Structure Probing of CUG Triplet Repeat RNA
  • FISH Protocol for Myotonic Dystrophy Type 1 Cells
  • Real Time Videomicroscopy and Semi-Automated Analysis of Brain Cell Culture Models of Trinucleotide Repeat Expansion Diseases
  • Primary Cultures of Pure Embryonic Dorsal Root Ganglia Sensory Neurons as a New Cellular Model for Friedreich’s Ataxia
  • GFP Reporters to Monitor Instability and Expression of Expanded CAG/CTG Repeats
  • Gene Therapy for Huntington's Disease Using Targeted Endonucleases.