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141107s2015 ne | s |||| 0|eng d |
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|a 9789401794213
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| 024 |
7 |
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|a 10.1007/978-94-017-9421-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Stress Response Pathways in Cancer :
|b From Molecular Targets to Novel Therapeutics /
|c edited by Georg T. Wondrak.
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| 250 |
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|a 1st ed. 2015.
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| 260 |
# |
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2015.
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| 300 |
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|a XII, 446 p. 56 illus., 52 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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|a Preface -- Introduction to cell stress responses in cancer: The big picture -- DNA repair dysregulation in cancer: From molecular mechanisms to synthetic-lethal opportunities -- Cell cycle checkpoint defects as anticancer targets: From molecular mechanisms to therapeutic opportunities -- p53 at the crossroads between stress response signaling and tumorigenesis: From molecular mechanisms to therapeutic opportunities -- Sirtuins as a double-edged sword in cancer: From molecular mechanisms to therapeutic opportunities -- MicroRNA regulated stress responses in cancer -- Senescence in oncogenesis: From molecular mechanisms to therapeutic opportunities -- Pro-senescence therapy for cancer: time for the clinic -- Integrating proteotoxic stress response pathways for induction of cell death in cancer cells: molecular mechanisms and opportunities -- The Hsp70 family of heat shock proteins in tumorigenesis: From molecular mechanisms to therapeutic opportunities -- The ubiquitin-proteasome system (UPS) as a cancer drug target: Emerging mechanisms and therapeutics -- Endoplasmatic reticulum stress in multiple myeloma: From molecular mechanisms to therapeutic opportunities -- Melanomagenic gene alterations viewed from a redox perspective: Molecular mechanisms and therapeutic opportunities -- Targeting hypoxic adaptations of cancer cells: Molecular mechanisms and therapeutic opportunities -- Targeting glycolytic adaptations of cancer cells: from molecular mechanisms to therapeutic opportunities -- At the crossroads between mitochondrial metabolite transport and apoptosis: VDAC1 as an emerging cancer drug target -- Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities -- Cell-nonautonomous ER stress-mediated dysregulation of immunity by cancer cells -- Index.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Cell biology.
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| 650 |
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|a Oncology .
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| 650 |
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4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Oncology.
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| 700 |
1 |
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|a Wondrak, Georg T.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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