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160822s2016 gw | s |||| 0|eng d |
| 020 |
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|a 9783319431574
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| 024 |
7 |
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|a 10.1007/978-3-319-43157-4
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Skin Stress Response Pathways :
|b Environmental Factors and Molecular Opportunities /
|c edited by Georg T. Wondrak.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
# |
# |
|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a IX, 457 p. 68 illus., 39 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Preface -- The skin lipidome under environmental stress – Technological platforms, molecular pathways and translational opportunities -- Squalene and skin barrier function: From molecular target to biomarker of environmental exposure -- Sunlight-induced DNA damage: molecular mechanisms and photoprotection strategies -- Urocanic Acid and Skin Photodamage: New Light on an Old Chromophore -- The Skin Extracellular Matrix as a Target of Environmental Exposure: Molecular Mechanisms, Prevention and Repair -- Nitric Oxide Derivatives and Skin Environmental Exposure to light: From Molecular Pathways to Therapeutic Opportunities -- Melanocortin 1 receptor (MC1R) as a global regulator of cutaneous UV responses: molecular interactions and opportunities for melanoma prevention -- The Cutaneous Melanocyte as a Target of Environmental Stressors: Molecular Mechanisms and Opportunities -- The Role of Epidermal p38 Signaling in Solar UV Radiation-induced Inflammation: Molecular Pathways and Preventive Opportunities -- UV-Induced Chemokines as Emerging Targets for Skin Cancer Photochemoprevention -- TLR3 and Inflammatory Skin Diseases: From Environmental Factors to Molecular Opportunities -- Sirtuins and stress response in skin cancer, aging, and barrier function -- Cutaneous Opioid Receptors and Stress Responses: Molecular Interactions and Opportunities for Therapeutic Intervention -- Regulation of Cutaneous Stress Response Pathways by the Circadian Clock: From Molecular Pathways to Therapeutic Opportunities -- Endocannabinoids and Skin Barrier Function: Molecular Pathways and Therapeutic Opportunities -- The aryl hydrocarbon receptor (AhR) as an environmental stress sensor and regulator of skin barrier function: Molecular mechanisms and therapeutic opportunities -- Biological cell protection by natural compounds, a second line of defense against solar radiation -- The Cutaneous Microbiota as a Determinant of Skin Barrier Function: Molecular Interactions and Therapeutic Opportunities -- Sensing Environmental Factors: The Emerging Role of Receptors in Epidermal Homeostasis and Whole-Body Health -- The Cutaneous Circadian Clock as a Determinant of Environmental Vulnerability: Molecular Pathways and Chrono-pharmacological Opportunities -- Psychological stress as a determinant of skin barrier function: Immunological pathways and therapeutic opportunities -- Index.
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| 650 |
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0 |
|a Medicine.
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| 650 |
1 |
4 |
|a Biomedicine, general.
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| 700 |
1 |
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|a Wondrak, Georg T.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|