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120730s2013 ne | s |||| 0|eng d |
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|a 9789400745315
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| 024 |
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|a 10.1007/978-94-007-4531-5
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Site-directed insertion of transgenes /
|c edited by Sylvaine Renault, Philippe Duchateau.
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| 250 |
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|a 1st ed. 2013.
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| 260 |
# |
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a XIV, 394 p. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Topics in Current Genetics,
|v 23
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|a Preface -- Section 1: Site–directed integration of transgenes -- 1 Transgene site-specific integration : troubles and solutions -- 2 : Designing non-viral targetd integrating vectors for genome enginnering in vertebrates -- 3: Gene targeting and homologous recombination in Saccharomyces cerevisiae4: Eucaryotic homologous recombination in mammalian cells -- 5 Engineered Zinc Finger Nucleases for Targeted Genome Editing -- 6: Engineered meganucleases for genome engineering purposes -- Section3: Integration based on Site-specific recombination -- 7 : Cre/loxP, Flp/FRT systems and pluripotent stem cell lines -- 8 : Site-specific recombination using C31 Integrase -- 9 : Modified transposases used for site-directed insertion of transgenes -- 10 : Targeted Plasmid Integration into the Human Genome by Engineered Recombinases -- 11: Gene site-specific insertion in plants -- 12 Site-directed insertion of transgenes in Drosophila -- 13. Nuclease Mediated Targeted Genome Modification in Mammalian Cells -- 14: Bio-applications derived from site-directed genome modification technologies.
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| 650 |
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|a Genetic engineering.
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| 650 |
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|a Gene therapy.
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| 650 |
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|a Medical genetics.
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| 650 |
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|a Gene expression.
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4 |
|a Genetic Engineering.
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| 650 |
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4 |
|a Gene Therapy.
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| 650 |
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4 |
|a Gene Function.
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| 650 |
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4 |
|a Gene Expression.
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| 700 |
1 |
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|a Renault, Sylvaine.
|e editor.
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| 700 |
1 |
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|a Duchateau, Philippe.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|