Smad Signal Transduction : Smads in Proliferation, Differentiation and Disease /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Dijke, Peter. (Editor ), Heldin, Carl-Henrik. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2006.
Edición:1st ed. 2006.
Colección:Proteins and Cell Regulation ; 5
Materias:
Tabla de Contenidos:
  • Molecular Evolution of Smad Proteins
  • C. Elegans TGF-? Signaling Pathways
  • Smads In Drosophila – Interpretation Of Graded Signals In Vivo
  • Delineating the TGF-?/Smad-Induced Cytostatic Response
  • Smads In Mesenchymal Differentiation
  • Smad Proteins in Apoptotic and Survival Signaling
  • TGF-?/SMAD Signaling in Epithelial to Mesenchymal Transition
  • Genetic Disruptions within the Murine Genome Reveal Numerous Roles of the Smad Gene Family in Development, Disease, and Cancer
  • Trafficking of Serine/Threonine Kinase Receptors and Smad Activation
  • Nucleocytoplasmic Shuttling of Smad Proteins
  • Structural Insights into Smad Function and Specificity
  • Regulation of Smad Function by Phosphorylation
  • Regulation of Smad Functions Through Ubiquitination and Sumoylation Pathways
  • Smad Transcriptional Co-Activators and Co-Repressors
  • Integration of Signaling Pathways Via Smad Proteins
  • Interplays Between The Smad and Map Kinase Signaling Pathways
  • Gene Expression Signatures of TGF-?/Smad-Induced Responses
  • Systems Biology Approaches to TGF-?/Smad Signaling
  • Inhibitory Smads: Mechanisms of Action and Roles in Human Diseases
  • Alterations in Smad Signaling in Carcinogenesis
  • TGF-? Receptor Kinase Inhibitors for the Treatment of Cancer
  • TGF-? Receptor Kinase Inhibitors for Treatment of Fibrosis.