Teratogenicity Testing : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Félix, Luís. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2018.
Edición:1st ed. 2018.
Colección:Methods in Molecular Biology, 1797
Materias:
Tabla de Contenidos:
  • An Overview of Teratology
  • Teratology Study Guidelines: An Overview
  • Biological Concerns on the Selection of Animal Models for Teratogenic Testing
  • The Validated Embryonic Stem Cell Test with Murine Embryonic Stem Cells
  • Human Pluripotent Stem Cells to Assess Developmental Toxicity in the Osteogenic Lineage
  • Chick Embryonic Cardiomyocytes Micromass System for Assessing Developmental Cardiotoxicity of Drugs
  • Flow Cytometry to Evaluate Potential Developmental Toxicants in the Embryonic Stem Cell
  • Morphology-Based Whole Embryo Culture for Developmental Toxicity of Drugs
  • Western Blot Methodologies for Analysis of In Vitro Protein Expression Induced by Teratogenic Agents
  • Manipulation of MicroRNAs in Cultured Mouse Embryos: Applications for Developmental Toxicology
  • Insights into the Phenotypic and Behavioral Effects of Teratogenic Drugs in Caenorhabditis elegans
  • Effect of Teratogens on Development of Drosophila melanogaster
  • Cellular Responses in Drosophila melanogaster Following Teratogen Exposure
  • Behavioral Teratogenesis in Drosophila melanogaster
  • Evaluation of the Teratogenicity of Pharmaceuticals Using FETAX
  • Histological Observation of Teratogenic Phenotypes Induced in Frog Embryo Assays
  • Visualization of Gene Expression Patterns by In Situ Hybridization on Early Stages of Development of Xenopus laevis
  • Analysis of Lethality and Malformations During Zebrafish (Danio rerio) Development
  • General Whole-Mount Immunohistochemistry of Zebrafish (Danio rerio) Embryos and Larvae Protocol
  • Geometric Morphometrics as a Tool to Evaluate Teratogenic Effects in Zebrafish (Danio rerio)
  • Live Metabolic Profile Analysis of Zebrafish Embryos Using a Seahorse XF 24 Extracellular Flux Analyzer
  • Behavioral Profiling of Zebrafish (Danio rerio) Larvae Following Teratogen Exposure
  • Omics in Zebrafish Teratogenesis
  • Proteomic Analysis of Zebrafish (Danio rerio) after Chemical Exposure
  • Immunohistochemical Assessment as a Tool for Investigating Developmental Toxicity in Zebrafish (Danio rerio)
  • Oxidative Stress Assessment in Zebrafish Larvae
  • Hemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo
  • Western Blot Analysis and Immunostaining for Prediction of Embryotoxicity in Mus musculus
  • Histological and Histochemical Profile for Teratological Assessment in Mus musculus
  • In Vivo Analysis of Apoptosis in Embryonic Hippocampus
  • Measurement of Mitochondrial Toxicity Parameters in Embryonic Hippocampus
  • Animal Tests for Evaluation of Cognitive Impairment in Neonatal Mouse
  • Methodology of Genotoxic and Teratogenic Studies in Rats
  • Whole Mount In Situ Hybridization and Morphometric Analysis in Rabbit Embryos
  • Glossary of Key Terms for Teratology.