The Hippo Signaling Pathway and Cancer /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Oren, Moshe. (Editor ), Aylon, Yael. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Materias:
Tabla de Contenidos:
  • Introduction
  • Merlin and Angiomotin in Hippo-Yap signaling
  • MST1/2 and other upstream signaling that affect Hippo pathway function
  • YAP1 uses its modular protein domains and conserved sequence motifs to orchestrate diverse repertoires of signaling
  • Regulation of YAP and TAZ transcription co-activators
  • Regulation of YAP and TAZ by epithelial plasticity
  • Hippo pathway and apoptosis
  • YAP and p73: a matter of mutual specificity in tumour suppression
  • The c-Abl/YAP/p73 apoptotic module and the Hippo pathway
  • Hippo in cell cycle and mitosis
  • Hippo and mouse models for cancer
  • Roles of Hippo signaling during mouse embryogenesis
  • Hippo Signaling and stem cells
  • Hippo signaling and organ size control
  • Hippo signaling in heart development
  • Cell competition and the Hippo pathway
  • Non-canonical roles from the Hippo pathway
  • Index.