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02513nam a22003135i 4500 |
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cr nn 008mamaa |
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130611s2013 xxu| s |||| 0|eng d |
| 020 |
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|a 9781627034111
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| 024 |
7 |
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|a 10.1007/978-1-62703-411-1
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Trinucleotide Repeat Protocols /
|c edited by Yoshinori Kohwi, Cynthia T. McMurray.
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| 250 |
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|a 2nd ed. 2013.
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| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
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| 300 |
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|a XIII, 296 p. 64 illus., 24 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1010
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| 505 |
0 |
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|a A Brief History of Triplet Repeat Disease -- Huntington's Disease and Cell Therapies: Past, Present and Future -- Transcranial Two-Photon Imaging of Synaptic Structures in the Cortex of Awake Head-Restrained Mice -- In vivo Imaging of Synapse Plasticity in the Mouse Motor Cortex -- Pluripotent Hybrid Stem Cells from Transgenic Huntington's Disease Monkey -- Mesenchymal Stem Cells for Trinucleotide Repeat Disorders -- Lentiviral-Mediated Gene Transfer of siRNAs for the Treatment of Huntington's Disease -- Purification of dFMR1-Containing Complexes Using Tandem Affinity Purification -- Combined FISH and Immunofluorescent Staining Methods to Co-localize Proteins and mRNA in Neurons and Brain Tissue -- Epigenetic Modifications of the FMR1 Gene -- The CGG Repeat and the FMR1 Gene -- Study of Oxidative Damage and Antioxidant Systems in Two Huntington´s Disease Rodent Models -- Regulation of Ataxin-1 Phosphorylation and Its Impact on Biology -- Towards Understanding Region-Specificity of Triplet Repeat Diseases: Coupled Immunohistology and Mass Spectrometry Imaging -- Antibodies and Intrabodies Against Huntingtin: Production and Screening of Monoclonals and Single-Chain Recombinant Forms -- Cell Recovery from DM1 Transgenic Mouse Tissue to Study (CTG)n Instability and DM1 Pathogenesis -- Markerless Modification of Trinucleotide Repeat Loci in BACs -- DRPLA: Recent Advances in Research Using Transgenic Mouse Models.
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| 650 |
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0 |
|a Molecular biology.
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| 650 |
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0 |
|a Gene expression.
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| 650 |
1 |
4 |
|a Molecular Medicine.
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| 650 |
2 |
4 |
|a Gene Expression.
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| 700 |
1 |
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|a Kohwi, Yoshinori.
|e editor.
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| 700 |
1 |
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|a McMurray, Cynthia T.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|