Transporters in Drug Development : Discovery, Optimization, Clinical Study and Regulation /
Autor Corporativo: | |
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Otros Autores: | , |
Formato: | eBook |
Lenguaje: | English |
Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2013.
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Edición: | 1st ed. 2013. |
Colección: | AAPS Advances in the Pharmaceutical Sciences Series,
7 |
Materias: |
Tabla de Contenidos:
- Membrane Transporters in ADME
- In Vitro Characterization of Transporter Mediated Permeability
- In Vitro Characterization of Interactions with Drug Transporting Proteins
- In Vivo Characterization of Interactions on Transporters
- Application of Targeted Proteomics in ADME for IVIVE
- Prediction of Transporter Mediated Drug-Drug Interaction from In Vitro Data
- Accounting for Transporters in Renal Clearance: Towards a Mechanistic Kidney Model (Mech KiM)
- Analysis of Intestinal Transporters
- Analysis of Hepatic Transport Proteins
- Analysis of Renal Transporters
- The Role of Transporters During Drug Development: Regulatory Science Perspective from the FDA
- Industrial Evaluation of Drug Transporters in ADME.