Transporters in Drug Development : Discovery, Optimization, Clinical Study and Regulation /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Sugiyama, Yuichi. (Editor ), Steffansen, Bente. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:AAPS Advances in the Pharmaceutical Sciences Series, 7
Materias:
Tabla de Contenidos:
  • Membrane Transporters in ADME
  • In Vitro Characterization of Transporter Mediated Permeability
  • In Vitro Characterization of Interactions with Drug Transporting Proteins
  • In Vivo Characterization of Interactions on Transporters
  • Application of Targeted Proteomics in ADME for IVIVE
  • Prediction of Transporter Mediated Drug-Drug Interaction from In Vitro Data
  • Accounting for Transporters in Renal Clearance: Towards a Mechanistic Kidney Model (Mech KiM)
  • Analysis of Intestinal Transporters
  • Analysis of Hepatic Transport Proteins
  • Analysis of Renal Transporters
  • The Role of Transporters During Drug Development: Regulatory Science Perspective from the FDA
  • Industrial Evaluation of Drug Transporters in ADME.