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130305s2013 ne | s |||| 0|eng d |
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|a 9789400759589
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| 024 |
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|a 10.1007/978-94-007-5958-9
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Tumor Dormancy, Quiescence, and Senescence, Volume 1 :
|b Aging, Cancer, and Noncancer Pathologies /
|c edited by M.A. Hayat.
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| 250 |
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|a 1st ed. 2013.
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| 260 |
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a XXIV, 324 p. 54 illus., 35 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Tumor Dormancy and Cellular Quiescence and Senescence, Aging, Cancer, and Noncancer Pathologies ;
|v 1
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| 505 |
0 |
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|a Preface.-I. Tumor dormancy -- Is tumor dormancy clinically relevant?- Microenvironmental influence on breast cancer Dormancy and metastasis -- Determination of breast cancer dormancy: analysis of Circulating free dna using snp 6.0 arrays -- Clonogenicity of cultured prostate cancer cells is controlled by dormancy : significance and comparison with cell culture models of breast cancer cell dormancy -- Dormancy and metastasis of melanoma cells to lymph Nodes, lung, and liver -- Late recurrence is a sign of melanoma dormancy: need of Life-long follow-up of elanoma patients. II. Quiescence -- Hematopoietic stem cell quiescence and long term Maintenance: role of scl/tal1 -- Regulation of muscle stem cell quiescent and Undifferentiated state: roles of hesr1 and hesr3 genes -- The kinase mirk/dyrk1b mediates a reversible quiescent State in a subset of ovarian, pancreatic, and colon cancers. III. Cellular senescence -- Stress -induced senescence: molecular pathways.-11 Accumulation of reactive oxygen species and induction Of premature senescence: role of ddb2 -- P21 mediates senescence by a mechanism involving accumulation of reactive oxygen species -- Role of micrornase and zeb1 downmodulation in oxidative Stress-induced apoptosis and senescence.- Hypoxic response in senescent brain is impaired: possible Contribution to neurodegeneration.-Enhancing reprogramming to pluripotency by controlling senescence -- Histone deacetylase inhibitor induces replicative Senescence of mesenchymal stem cells -- Senescence arrest of endopolyploid cells renders Senescence into one mechanism for positive tumorigenesis -- The two faces of senescence-associated epigenetic Alterations: tumor suppressors and oncogenic drivers.- Chemotherapy- and radiation-induced accelerated senescence: implications for treatment response, tumor progression, and cancer survivorship -- Suppression of cellular senescence in glioblastoma: role Of src homology domain-containing phosphatase 2 -- Chemotherapy of malignant pleural mesothelioma induces both senescence and apoptosis -- Microrna as a modulator of cell proliferation and Senescence: role in lung cancer cells -- Role of senescence induction in cancer therapy -- Cellular senescence limits the extent of fibrosis Following liver damage -- Formation of secretory senescent cells in prostate tumors: the role of androgen receptor activity and cell cycle regulation.-Index .
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| 650 |
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|a Cancer research.
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| 650 |
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|a Stem cells.
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| 650 |
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|a Public health.
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| 650 |
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|a Cancer Research.
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| 650 |
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4 |
|a Stem Cells.
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| 650 |
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4 |
|a Public Health.
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| 700 |
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|a Hayat, M.A.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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