The Structural Basis of Arrestin Functions /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2017.
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| Edición: | 1st ed. 2017. |
| Materias: |
Tabla de Contenidos:
- Arrestins: discovery of the family and functional role of conformational flexibility
- Overview of arrestin-mediated signaling with receptors and non-receptor binding partners
- Initial crystallographic studies of visual arrestin: insights and perspectives
- Structural basis for b-arrestins in GPCR trafficking
- Arrestin-3: the structural basis of lower receptor selectivity
- Phosphate sensor and construction of phosphorylation-independent arrestins
- Comprehensive analysis of the role of arrestin residues in receptor binding
- How arrestin recognizes and binds active GPCRs
- Localization of conformational dynamics of arrestins by HDX-MS
- GPCR footprint on arrestins and manipulation of receptor specificity
- The structure of the polar core mutant R175E and its functional implications
- Active conformations of arrestins: expected and unexpected changes
- The arrestin-receptor complex: exciting answers and new questions
- Scaffolding c-Jun N-terminal kinase cascades: mechanistic insights from the reconstituted arrestin-JNK cascades
- Arrestin-dependent ERK activation and its disruption
- The functional role of the conformational changes in arrestin upon activation
- Is signaling specificity encoded in arrestin conformation?
- Monofunctional elements of multi-functional arrestin proteins
- Arrestins in cell death.