War in the Body : The Evolutionary Arms Race Between HIV and the Human Immune System and the Implications for Vaccines /

Detalles Bibliográficos
Autores principales: Wick, W David. (Autor), Yang, Otto O. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Materias:
Tabla de Contenidos:
  • The HIV Infection model
  • The CTL Model
  • Simulating an HIV Infection In Vivo
  • The Escape Formula
  • Early and Late Escapes
  • Understanding Escape
  • More Topics about Escape from Immune Control
  • HIV's Cloaking Device: The Fascinating Story of Nef
  • Retroviral Sex and Escape
  • The Ne Business Again and a Proposed Experiment
  • Can a T-cell Vaccine Block Escape?
  • The STEP Trial and the Future of T-cell Vaccines
  • Short Tutorial on Dynamical Models
  • Deterministic Modeling: A Cautionary Example
  • The Infection Model Defined
  • The CTL Model Defined
  • On Simulation Techniques
  • Derivation of the Escape Formula
  • Statistics of the Mutant Lineage in Classical Genetics
  • Extinction Probabilities with Extra Poisson Variation
  • Computing the Boundaries
  • Co-existence or Replacement?
  • The Nef-Deletion Threshold Formulas
  • Modeling Retroviral Sex.