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121116s2013 xxu| s |||| 0|eng d |
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|a 9781627032360
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| 024 |
7 |
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|a 10.1007/978-1-62703-236-0
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a p53 Protocols /
|c edited by Sumitra Deb, Swati Palit Deb.
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| 250 |
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|a 2nd ed. 2013.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
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| 300 |
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|a X, 238 p. 51 illus., 33 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 962
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| 505 |
0 |
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|a Detecting and Quantifying p53 Isoforms at mRNA Level in Cell Lines and Tissues -- Detecting p53 Isoforms at Protein Level -- Autophagy, Senescence and Apoptosis -- p53 and Cell Cycle Effects after DNA Damage -- p53 Ubiquitination and Proteasomal Degradation.-Identification of p53 in Mitochondria.-Identification of Novel Mutant p53 Interacting Proteins by Proteomic Analysis.-Identification of Small Molecules Affecting p53-MDM2/MDMX Interaction by Fluorescence Polarization -- Determine the Effect of p53 on Chemosensitivity.-Measurement of Chemosensitivity and Growth Rate in p53 Expressing Cells -- Mutant p53 in Cell Adhesion and Motility -- Use of the DNA Fiber Spreading Technique to Detect the Effects of Mutant p53 on DNA Replication -- Generation of p53-deficient Induced Pluripotent Stem Cells (iPS) from Mouse Embryo Fibroblasts -- p53 Actions on MicroRNA Expression and Maturation Pathway -- Isolation and Characterization of Murine Multipotent Lung Stem Cells -- Generation of p53 Knock-down Cell Lines.-ChIP for Identification of p53 Responsive DNA Promoters -- ChIP-on-chip to Identify Mutant p53 Targets -- ChIP Sequencing to Identify p53 Targets -- The p53-Mdm2 Loop: A Critical Juncture of Stress Response.
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| 650 |
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|a Proteins .
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| 650 |
1 |
4 |
|a Protein Science.
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| 700 |
1 |
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|a Deb, Sumitra.
|e editor.
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| 700 |
1 |
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|a Deb, Swati Palit.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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