The p53 Tumor Suppressor Pathway and Cancer
| Corporate Author: | |
|---|---|
| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
New York, NY :
Springer US : Imprint: Springer,
2005.
|
| Edition: | 1st ed. 2005. |
| Series: | Protein Reviews ;
2 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/0-387-30127-5 |
Table of Contents:
- The p53 Network
- The Three-Dimensional Structure of p53
- Transcriptional Activation by p53: Mechanisms and Targeted Genes
- Transcriptional Repression by the p53 Tumor Suppressor Protein
- Posttranslational Modifications of p53: Upstream Signaling Pathways
- p53 in Human Cancer - Somatic and Inherited Mutations and Mutation-independent Mechanisms
- MDM2 and MDMX Regulators of p53 Activity
- p53 Family Members: p63 and p73
- The Oncogenic Activity of p53 Mutants
- Therapeutic Strategies Based on Pharmacological Modulation of p53 Pathway.