N-Acetylaspartate A Unique Neuronal Molecule in the Central Nervous System /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Moffett, John. (Editor ), Tieman, Suzannah B. (Editor ), Weinberger, Daniel R. (Editor ), Coyle, Joseph T. (Editor ), Namboodiri, Aryan M. A. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer US : Imprint: Springer, 2006.
Edición:1st ed. 2006.
Materias:
Acceso en línea:https://doi.org/10.1007/0-387-30172-0
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245 1 0 |a N-Acetylaspartate  |b A Unique Neuronal Molecule in the Central Nervous System /  |c edited by John Moffett, Suzannah B. Tieman, Daniel R. Weinberger, Joseph T. Coyle, Aryan M. A. Namboodiri. 
250 |a 1st ed. 2006. 
260 # # |a New York, NY :  |b Springer US :  |b Imprint: Springer,  |c 2006. 
300 |a XVII, 375 p.  |b online resource. 
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505 0 |a A Brief Overview of N-Acetylaspartate and N-Acetylaspartylglutamate -- Expression of N-Acetylaspartate and N-Acetylaspartylglutamate in the Nervous System -- N-Acetylaspartate Metabolism in Neural Cells -- Naa Synthesis and Functional Roles -- Identity of the High-Affinity Sodium/Carboxylate Cotransporter NaC3 as the N-Acetyl-L-Aspartate Transporter -- Canavan Disease: Studies on the Knockout Mouse -- Functions Of N-Acetylaspartate and N-Acetylaspartylglutamate in Brain -- Control of Brain Volume during Hypoosmolality and Hyperosmolality -- Physiological Role of N-Acetylaspartate -- Defective Myelin Lipid Synthesis as a Pathogenic Mechanism of Canavan Disease -- Mutation Analysis of the Aspartoacylase Gene in Non-Jewish Patients with Canavan Disease -- Does ASPA Gene Mutation in Canavan Disease Alter Oligodendrocyte Development? -- Quantitation of NAA in the Brain by Magnetic Resonance Spectroscopy -- N-Acetyl-L-Aspartate in Multiple Sclerosis -- NAA and Higher Cognitive Function in Humans -- In Vivo NMR Measures of NAA and the Neurobiology of Schizophrenia -- N-Acetylaspartate as a Marker of Neuronal Injury in Neurodegenerative Disease -- Regulation of NAA-Synthesis in the Human Brain in Vivo: Canavan’s Disease, Alzheimer’s Disease and Schizophrenia -- Magnetic Resonance Spectroscopy for Monitoring Neuronal Integrity in Amyotrophic Lateral Sclerosis -- Hypoacetylaspartia: Clinical and Biochemical Follow-Up of a Patient -- Cellular Localization of NAAG -- Synthesis of N-Acetylaspartylglutamate (NAAG) and N-Acetylaspartate (NAA) in Axons and Glia of the Crayfish Medial Giant Nerve Fiber -- NAAG as a Neurotransmitter -- Glutamate Carboxypeptidase II (NAALADase) Inhibition as a Novel Therapeutic Strategy -- N-Acetylaspartylglutamate (NAAG) in Spinal Cord Injury and Disease -- N-Acetylaspartylglutamate (NAAG) in Pelizaeusmerzbacher Disease -- Concluding Remarks. 
650 0 |a Neurosciences. 
650 1 4 |a Neurosciences. 
700 1 |a Moffett, John.  |e editor. 
700 1 |a Tieman, Suzannah B.  |e editor. 
700 1 |a Weinberger, Daniel R.  |e editor. 
700 1 |a Coyle, Joseph T.  |e editor. 
700 1 |a Namboodiri, Aryan M. A.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
856 4 0 |u https://doi.org/10.1007/0-387-30172-0