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03112nam a22003255i 4500 |
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978-0-387-30172-3 |
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20190619192834.0 |
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100301s2006 xxu| s |||| 0|eng d |
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|a 9780387301723
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|a 10.1007/0-387-30172-0
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a N-Acetylaspartate
|b A Unique Neuronal Molecule in the Central Nervous System /
|c edited by John Moffett, Suzannah B. Tieman, Daniel R. Weinberger, Joseph T. Coyle, Aryan M. A. Namboodiri.
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|a 1st ed. 2006.
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|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 2006.
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|a XVII, 375 p.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a A Brief Overview of N-Acetylaspartate and N-Acetylaspartylglutamate -- Expression of N-Acetylaspartate and N-Acetylaspartylglutamate in the Nervous System -- N-Acetylaspartate Metabolism in Neural Cells -- Naa Synthesis and Functional Roles -- Identity of the High-Affinity Sodium/Carboxylate Cotransporter NaC3 as the N-Acetyl-L-Aspartate Transporter -- Canavan Disease: Studies on the Knockout Mouse -- Functions Of N-Acetylaspartate and N-Acetylaspartylglutamate in Brain -- Control of Brain Volume during Hypoosmolality and Hyperosmolality -- Physiological Role of N-Acetylaspartate -- Defective Myelin Lipid Synthesis as a Pathogenic Mechanism of Canavan Disease -- Mutation Analysis of the Aspartoacylase Gene in Non-Jewish Patients with Canavan Disease -- Does ASPA Gene Mutation in Canavan Disease Alter Oligodendrocyte Development? -- Quantitation of NAA in the Brain by Magnetic Resonance Spectroscopy -- N-Acetyl-L-Aspartate in Multiple Sclerosis -- NAA and Higher Cognitive Function in Humans -- In Vivo NMR Measures of NAA and the Neurobiology of Schizophrenia -- N-Acetylaspartate as a Marker of Neuronal Injury in Neurodegenerative Disease -- Regulation of NAA-Synthesis in the Human Brain in Vivo: Canavan’s Disease, Alzheimer’s Disease and Schizophrenia -- Magnetic Resonance Spectroscopy for Monitoring Neuronal Integrity in Amyotrophic Lateral Sclerosis -- Hypoacetylaspartia: Clinical and Biochemical Follow-Up of a Patient -- Cellular Localization of NAAG -- Synthesis of N-Acetylaspartylglutamate (NAAG) and N-Acetylaspartate (NAA) in Axons and Glia of the Crayfish Medial Giant Nerve Fiber -- NAAG as a Neurotransmitter -- Glutamate Carboxypeptidase II (NAALADase) Inhibition as a Novel Therapeutic Strategy -- N-Acetylaspartylglutamate (NAAG) in Spinal Cord Injury and Disease -- N-Acetylaspartylglutamate (NAAG) in Pelizaeusmerzbacher Disease -- Concluding Remarks.
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650 |
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|a Neurosciences.
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650 |
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|a Neurosciences.
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1 |
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|a Moffett, John.
|e editor.
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1 |
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|a Tieman, Suzannah B.
|e editor.
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700 |
1 |
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|a Weinberger, Daniel R.
|e editor.
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700 |
1 |
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|a Coyle, Joseph T.
|e editor.
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700 |
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|a Namboodiri, Aryan M. A.
|e editor.
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710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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|u https://doi.org/10.1007/0-387-30172-0
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