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Microorganisms and Autoimmune Diseases

Microorganisms and Autoimmune Diseases

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Friedman, Herman. (Editor), Rose, Noel R. (Editor), Bendinelli, Mauro. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 1996.
Edition:1st ed. 1996.
Series:Infectious Agents and Pathogenesis,
Subjects:
Immunology.
Medical microbiology.
Plant science.
Botany.
Animal anatomy.
Microbial ecology.
Medical Microbiology.
Plant Sciences.
Animal Anatomy / Morphology / Histology.
Microbial Ecology.
Online Access:https://doi.org/10.1007/978-1-4613-0347-3
Table of Contents:
  • 1. Bacterial Heat-Shock Proteins and Autoimmune Disease
  • 1. Introduction
  • 2. Peripheral Tolerance, Autoimmunity, and Environmental Bacteria
  • 3. Experimental Models Support a Critical Role of Specific Immunity in Autoimmune Diseases
  • 4. HSP60 and the Inhibition of Experimental Arthritis
  • 5. Responses to Human HSP60 in Juvenile Chronic Arthritis
  • 6. Lessons for the Development of Specific Immunotherapy in Autoimmunity
  • References
  • 2. Streptococci and Rheumatic Fever
  • 1. Introduction
  • 2. Historical Perspective
  • 3. Clinical Features
  • 4. Etiology: The Group A Streptococcus
  • 5. Epidemiology and Host Susceptibility
  • 6. Autoimmune Pathogenesis of Acute Rheumatic Fever
  • 7. Animal Models of Rheumatic Heart Disease
  • 8. Treatment and Prevention
  • References
  • 3. HLA-B27, Enteric Bacteria, and Ankylosing Spondylitis
  • 1. Introduction
  • 2. One- and Two-Gene Theories
  • 3. Description of HLA-B27-Associated Disease Markers in the Pathogenesis of Ankylosing Spondylitis
  • 4. Evidence for HLA-B27-Restricted Cytotoxic T Lymphocytes in the Pathogenesis of Ankylosing Spondylitis and Other Seronegative Arthropathies
  • 5. Conclusions and Future Directions
  • References
  • 4. Triggering of Autoimmune Antibody Responses in Syphilis
  • 1. Introduction
  • 2. Overview of the Disease
  • 3. Immune Complexes and Autoimmune Responses in Syphilis
  • 4. Polyclonal B-Cell Activation
  • 5. Idiotypic Networks
  • 6. Molecular Mimicry
  • 7. Concluding Remarks
  • References
  • 5. Viruses and Diabetes Mellitus
  • 1. Introduction
  • 2. Viruses and Autoimmune Diabetes
  • 3. Interferon and Diabetes
  • 4. Molecular Mimicry between Viruses and Beta-Cell Autoantigens
  • 5. Transgenic Models of Virus-Induced Diabetes
  • 6. Concluding Remarks
  • References
  • 6. The Role of Coxsackie B Viruses in the Pathogenesis of Type I Diabetes
  • 1. Introduction
  • 2. Epidemiological Studies
  • 3. Difficulties Encountered in Epidemiological Studies on the Relationship between Coxsackie B Viral Infections and IDDM
  • 4. Case Reports and in Vitro Studies on Human Islet Cells
  • 5. Animal Studies
  • 6. Mechanisms for Coxsackie B Virus-Induced Diabetes
  • 7. Concluding Remarks
  • References
  • 7. Neuropathic Viruses and Autoimmunity
  • 1. Neurotropic Infection
  • 2. Virus Entry and Infection
  • 3. Acute Infection
  • 4. Persistent Viral Infections
  • 5. Viral Complications of Immunosuppression
  • 6. Parainfectious Syndromes
  • 7. Discussion and Conclusions
  • References
  • 8. Postmeasles Encephalomyelitis
  • 1. Introduction
  • 2. Postmeasles Encephalomyelitis
  • 3. Viral Induction of Autoimmune Disease
  • 4. Autoimmune Destruction of Myelin
  • 5. Additional Mechanisms of Viral Demyelination
  • 6. Conclusion
  • References
  • 9. Epstein-Barr Virus and Autoimmunity
  • 1. Introduction
  • 2. The Epstein-Barr Virus
  • 3. EBV-Related Diseases
  • 4. Autoimmune Diseases Possibly Related to EBV
  • 5. Autoimmunity in Infectious Mononucleosis
  • 6. Conclusions
  • References
  • 10. Retroviruses and Autoimmunity
  • 1. Introduction
  • 2. Retroviruses and Autoimmune Disease
  • 3. General Biology of Retroviruses
  • 4. Classic Autoimmune Disorders and Associations with Retroviruses
  • 5. Summary
  • References
  • 11. Autoimmunity in Chagas Disease
  • 1. Introduction
  • 2. Uncommon Molecular Features of Trypanosoma cruzi
  • 3. The Paradox of Antigen-Driven Delayed-Type Hypersensitivity
  • 4. The Paradox of the Severe Forms of Acute Chagas Disease in Santiago del Estero Infants
  • 5. Downregulation of the Immune Response
  • 6. Autoreactive Organ-Specific Delayed-Type Hypersensitivity and Autoantibodies
  • References
  • 12. Infection and Endocrine Autoimmunity
  • 1. Introduction
  • 2. The Potential Role of Infection in Autoimmunity
  • 3. Autoimmune Thyroid Disease
  • 4. Pituitary and Polyendocrine Autoimmunity
  • 5. Conclusion
  • References
  • 13. Infection as a Precursor to Autoimmunity
  • 1. Introduction
  • 2. Myocarditis
  • 3. An Animal Model of Myocarditis
  • 4. Genetics of Autoimmune Myocarditis
  • 5. The Role of Cytokines
  • 6. Myosin as Autoantigen
  • 7. Discussion
  • References.

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