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02538nam a22003015i 4500 |
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978-1-4939-6346-1 |
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20191026152323.0 |
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cr nn 008mamaa |
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160812s2016 xxu| s |||| 0|eng d |
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|a 9781493963461
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7 |
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|a 10.1007/978-1-4939-6346-1
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a High-Throughput Screening Assays in Toxicology
|c edited by Hao Zhu, Menghang Xia.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2016.
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| 300 |
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|a XII, 175 p. 50 illus., 32 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 1473
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| 505 |
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|a Monitoring Ligand-Activated Protein-Protein Interactions Using Bioluminescent Resonance Energy Transfer (BRET) Assay -- Mitochondrial Membrane Potential Assay -- Using β-Lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway -- Quantitative High-Throughput Luciferase Screening in Identifying CAR Modulators -- Transactivation and Coactivator Recruitment Assays for Measuring Farnesoid X Receptor Activity -- Cell-Based Assay for Identifying the Modulators of Antioxidant Response Element Signaling Pathway -- Study Liver Cytochrome P450 3A4 Inhibition and Hepatotoxicity Using DMSO-Differentiated HuH-7 Cells -- Determination of Histone H2AX Phosphorylation in DT40 Cells -- High-Throughput and High Content Micronucleus Assay in CHO-K1 Cells -- Better, Faster, Cheaper: Getting the Most Out of High-Throughput Screening with Zebrafish -- Fast Functional Germline and Epigenetic Assays in the Nematode <Caenorhabditis elegans -- A Quantitative High-Throughput Screening Data Analysis Pipeline for Activity Profiling -- Correction of Microplate Data from High-Throughput Screening -- CurveP Method for Rendering High-Throughput Screening Dose-Response Data into Digital Fingerprints -- Accounting Artifacts in High-Throughput Toxicity Assays -- Accessing the High-Throughput Screening Data Landscape -- Curating and Preparing High Throughput Screening Data for Quantitative Structure Activity Relationship Modeling.
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| 650 |
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|a Pharmacology.
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| 650 |
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4 |
|a Pharmacology/Toxicology.
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| 700 |
1 |
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|a Zhu, Hao.
|e editor.
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| 700 |
1 |
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|a Xia, Menghang.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-1-4939-6346-1
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