Novel Anticancer Drug Protocols
| Autor Corporativo: | |
|---|---|
| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2003.
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| Edición: | 1st ed. 2003. |
| Colección: | Methods in Molecular Medicine,
85 |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1385/1592593801 |
Tabla de Contenidos:
- Overview of Novel Anticancer Drug Targets
- Kinase Inhibitor Discovery Protocols
- Biomarker Assays for Phosphorylated MAP Kinase
- Assays for Cyclin-Dependent Kinase Inhibitors
- Identifying Inhibitors of ATM and ATR Kinase Activities
- Angiogenesis and Metastasis Protocols
- The Rat Aortic Ring Assay for In Vitro Study of Angiogenesis
- Real Time In Vivo Quantitation of Tumor Angiogenesis
- Use of Tumor-Activated Hepatic Stellate Cell as a Target for the Preclinical Testing of Anti-Angiogenic Drugs Against Hepatic Tumor Development
- Cell Motility, Adhesion, Homing, and Migration Assays in the Studies of Tyrosine Kinases
- Inflammatory Response of Tumor-Activated Hepatic Sinusoidal Endothelium as a Target for the Screening of Metastasis Chemopreventive Drugs
- Binding Assay for Selectins
- Determination of Peak Serum Levels and Immune Response to the Humanized Anti-Ganglioside Antibody-Interleukin-2 Immunocytokine
- Immunohistochemical Assays in the Clinical Setting
- Immunohistochemical Determination of EGFR-Tyrosine Kinase Inhibition in Clinical Samples
- Immunohistochemical Assays of Farnesyltransferase Inhibition in Patient Samples
- Protein Chaperoning/Degradation Protocols
- Assays for HSP90 and Inhibitors
- Assays for Proteasome Inhibition
- Protein-Protein and Protein-DNA Interactions
- The Mammalian Two-Hybrid Assay for Detection of Coactivator-Nuclear Receptor Interactions
- Preparation of DNA-Protein Complexes Suitable for Spectroscopic Analysis
- Antisense
- Antisense Oligonucleotide Inhibitors of MDM2 Oncogene Expression
- Genomics
- Pharmacogenetic Analysis of Clinically Relevant Genetic Polymorphisms
- Gene Expression Microarrays
- Methods for Isolation and Genetic Analysis of Circulating Tumor DNA in Patient Plasma
- Cell Lifespan/Longevity
- The Use of Early Sea Urchin Embryos in Anticancer Drug Testing
- In Vivo Imaging
- PET Screening of Anticancer Drugs
- Miscellaneous Protocols
- Assays for In Vitro and In Vivo Synergy
- Flow Cytometric Methods for Detection and Quantification of Apoptosis
- Assays for Neoplastic Cell Enrichment in Bone Marrow Samples.