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02250nam a22002895i 4500 |
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978-1-59259-429-0 |
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20190618101642.0 |
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cr nn 008mamaa |
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100301s2004 xxu| s |||| 0|eng d |
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|a 9781592594290
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| 024 |
7 |
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|a 10.1385/1592594298
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Suicide Gene Therapy
|b Methods and Reviews /
|c edited by Caroline J. Springer.
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| 250 |
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|a 1st ed. 2004.
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| 260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2004.
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| 300 |
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|a XIV, 555 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Medicine,
|v 90
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|a to the Background, Principles, and State of the Art in Suicide Gene Therapy -- to Vectors for Suicide Gene Therapy -- Construction of VNP20009 -- Nonreplicating DNA Viral Vectors for Suicide Gene Therapy -- Replication-Selective Oncolytic Adenoviruses -- Retroviral Vectors for Suicide Gene Therapy -- Nonviral Liposomes -- Peptide- and Polymer-Based Gene Delivery Vehicles -- Design of Prodrugs for Suicide Gene Therapy -- Cytochrome P450-Based Gene Therapies for Cancer -- Tumor Sensitization to Purine Analogs by E. coli PNP -- Enzyme-Prodrug Systems -- Enzyme-Prodrug Systems -- Methods to Improve Efficacy in Suicide Gene Therapy Approaches -- Extracellular ?-Glucuronidase for Gene-Directed Enzyme-Prodrug Therapy -- Enhancement of Suicide Gene Prodrug Activation by Random Mutagenesis -- Combination Suicide Gene Therapy -- Immune Response to Suicide Gene Therapy -- Targeting Cancer With Gene Therapy Using Hypoxia as a Stimulus -- Radiation-Activated Antitumor Vectors -- In Vitro and In Vivo Models for Evaluation of GDEPT -- Suicide Gene Therapy in Liver Tumors -- Clinical Trials With GDEPT -- The Nitroreductase/CB1954 Enzyme-Prodrug System -- Side Effects of Suicide Gene Therapy -- Antibody-Directed Enzyme-Prodrug Therapy -- Bioreductive Prodrugs for Cancer Therapy.
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| 650 |
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|a Oncology .
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| 650 |
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|a Oncology.
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| 700 |
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|a Springer, Caroline J.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1385/1592594298
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