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02073nam a22003015i 4500 |
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978-1-59259-434-4 |
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20190618121932.0 |
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cr nn 008mamaa |
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100301s2004 xxu| s |||| 0|eng d |
| 020 |
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|a 9781592594344
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| 024 |
7 |
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|a 10.1385/1592594344
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Mammalian Artificial Chromosomes
|b Methods and Protocols /
|c edited by Vittorio Sgaramella, Sandro Eridani.
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| 250 |
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|a 1st ed. 2004.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2004.
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| 300 |
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|a XI, 269 p. 63 illus., 2 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 240
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| 505 |
0 |
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|a From Natural to Artificial Chromosomes -- Methodologies Applied to Domestic Animal Chromosomes -- Mapping of the Hotspots of Recombination in Human DNA Cloned as Yeast Artificial Chromosomes -- Genomic Imprinting and Its Effects on Genes and Chromosomes in Mammals -- Centromeres and Neocentromeres -- Identification of Start Sites of Bi-Directional DNA Synthesis at Eukaryotic DNA Replication Origins -- Telomere Length Analysis and In Vitro Telomerase Assay -- Telomerization of Mammalian Cells and Transplantation of Telomerized Cells in Immunodeficient Mice -- Chromosome-Based Vectors for Mammalian Cells -- Mammalian Artificial Chromosome Formation in Human Cells After Lipofection of a PAC Precursor -- Use of Natural and Artificial Chromosome Vectors for Animal Transgenesis -- Pronuclear Microinjection of Purified Artificial Chromosomes for Generation of Transgenic Mice -- Modification of Human Bacterial Artificial Chromosome Clones for Functional Studies and Therapeutic Applications.
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| 650 |
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|a Human genetics.
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| 650 |
1 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Sgaramella, Vittorio.
|e editor.
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| 700 |
1 |
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|a Eridani, Sandro.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1385/1592594344
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