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02674nam a22002895i 4500 |
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978-1-59259-823-6 |
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20190618021703.0 |
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cr nn 008mamaa |
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100301s2005 xxu| s |||| 0|eng d |
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|a 9781592598236
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|a 10.1385/1592598234
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Oligonucleotide Synthesis
|b Methods and Applications /
|c edited by Piet Herdewijn.
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| 250 |
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|a 1st ed. 2005.
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| 260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2005.
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| 300 |
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|a XVI, 436 p. 142 illus.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 288
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|a Synthesis of DNA Using a New Two-Step Cycle -- RNA Synthesis Using 2?-O-(Tert-Butyldimethylsilyl) Protection -- RNA Oligonucleotide Synthesis Via 5?-Silyl-2?-Orthoester Chemistry -- Dimethylthiarum Disulfide -- Assay for Evaluating Ribonuclease H-Mediated Degradation of RNA-Antisense Oligonucleotide Duplexes -- Di- and Oligonucleotide Synthesis Using H-Phosphonate Chemistry -- Solid-Phase Synthesis of Circular Oligonucleotides -- Locked Nucleic Acid Synthesis -- Synthesis of DNA Mimics Representing HypNA-pPNA Hetero-Oligomers -- Base-Modified Oligonucleotides With Increased Duplex Stability -- of Hypermodified Nucleotides in RNA -- Chemical Methods for Peptide-Oligonucleotide Conjugate Synthesis -- Biotin-Labeled Oligonucleotides With Extraordinarily Long Tethering Arms -- Universal Labeling Chemistry for Nucleic Acid Detection on DNA Chips -- Postsynthetic Functionalization of Triple Helix-Forming Oligonucleotides -- Fluorescence-Based On-Line Detection as an Analytical Tool in RNA Electrophoresis -- Design and Optimization of Molecular Beacon Real-Time Polymerase Chain Reaction Assays -- High-Throughput Production of Optimized Primers (Fimers) for Whole-Genome Direct Sequencing -- Nonenzymatic Template-Directed RNA Synthesis -- DNase I Footprinting of Small Molecule Binding Sites on DNA -- Gene Targeting Using Peptide Nucleic Acid -- Nucleic Acid Library Construction Using Synthetic DNA Constructs -- In Vitro Selection From Combinatorial Nucleic Acid Libraries -- In Vitro Selection Procedures for Identifying DNA and RNA Aptamers Targeted to Nucleic Acids and Proteins -- Short Double-Stranded Ribonucleic Acid as Inhibitor of Gene Expression by the Interference Mechanism.
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| 650 |
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|a Pharmacy.
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| 650 |
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|a Pharmacy.
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| 700 |
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|a Herdewijn, Piet.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1385/1592598234
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