The G Protein-Coupled Receptors Handbook

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Devi, Lakshmi A. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2005.
Edición:1st ed. 2005.
Colección:Contemporary Clinical Neuroscience
Materias:
Acceso en línea:https://doi.org/10.1007/978-1-59259-919-6
Tabla de Contenidos:
  • GPCRs: Structure and Function
  • Structure—Function Relationships in G Protein-Coupled Receptors
  • Molecular Mechanisms Involved in the Activation of Rhodopsin-Like Seven-Transmembrane Receptors
  • GPCR Folding and Maturation
  • Regulated Membrane Trafficking and Proteolysis of GPCRs
  • GPCR Activity and Its Regulators
  • Heterotrimeric G Proteins and Their Effector Pathways
  • RGS Proteins
  • G Protein-Coupled Receptor Kinases
  • Regulators of GPCR Activity
  • GPCR Interacting Proteins
  • GPCR Dimerization/Oligomerization
  • Biophysical and Biochemical Methods to Study GPCR Oligomerization
  • Oligomerization Domains of G Protein-Coupled Receptors
  • Functional Complementation and the Analysis of GPCR Dimerization
  • The Role of Oligomerization in G Protein-Coupled Receptor Maturation
  • Receptor Oligomerization and Trafficking
  • Modulation of Receptor Pharmacology by G Protein-Coupled Receptor Dimerization
  • Recent Developments in Drug Discovery
  • Role of Heteromeric GPCR Interactions in Pain/Analgesia
  • Conformational Plasticity of GPCR Binding Sites
  • De-Orphanizing GPCRs and Drug Development.