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02886nam a22003015i 4500 |
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978-1-59259-950-9 |
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20190618092007.0 |
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cr nn 008mamaa |
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100301s2005 xxu| s |||| 0|eng d |
| 020 |
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|a 9781592599509
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| 024 |
7 |
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|a 10.1385/1592599508
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
4 |
|a The Orexin/Hypocretin System
|b Physiology and Pathophysiology /
|c edited by Seiji Nishino, Takeshi Sakurai.
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| 250 |
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|a 1st ed. 2005.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2005.
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| 300 |
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|a 416 p. 151 illus., 9 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Contemporary Clinical Neuroscience
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|a History -- History and Overview of Orexin/Hypocretin Research -- Overview of the Orexin/Hypocretin Neuronal System -- Orexin and Orexin Receptors -- Orexin Projections and Localization of Orexin Receptors -- Neuronal Responses to Hypocretin/Orexin -- Afferent System of Orexin Neurons -- Assessment of Orexin/Hypocretin Functions in Tissue and Biological Fluids -- Hypocretin Measurements in the CSF, and Blood and Brain Tissue -- Hypocretin Receptor-Activated G Proteins Revealed by [35S]GTP?S Autoradiography -- Physiology -- Orexin System and Feeding Behavior -- Orexins and the Autonomic Nervous System -- Neuroendocrine Role of the Orexins (Hypocretins) -- The Orexin/Hypocretin System and Stress and Emotion -- Physiology -- Hypocretin as a Wakefulness Regulatory Peptide -- Hypocretin/Orexin Tonus and Vigilance Control -- Hypocretin System and Aminergic and Cholinergic Systems in the Control of Vigilance -- Orexin and Hypothalamic Control of Sleep and Waking -- Hypocretin/Orexin and Motor Function -- Pathophysiology: Narcolepsy and Orexin/Hypocretin Deficiency -- Overview of Human Narcolepsy -- Canine Models of Narcolepsy -- Rodent Models of Human Narcolepsy-Cataplexy -- Pathophysiology: Narcolepsy and Orexin/Hypocretin Deficiency -- Hypocretin Deficiency in Human Narcolepsy -- Hypocretin Status in Neurological Disorders in Relation to Excessive Sleepiness and Cataplexy -- Hypocretin Measures in Psychiatric Disorders -- Neuroendocrinology of Human Narcolepsy -- Narcolepsy and Autoimmunity -- Pathophysiology: Narcolepsy and Orexin/Hypocretin Deficiency -- Pharmacology of Hypocretin/Orexin Peptides and Small Molecules -- Rescue of Narcoleptic Orexin Neuron-Ablated Mice by Ectopic Overexpression of Orexin Peptides -- Hypocretin/Orexin Replacement Therapy in Hypocretin/Orexin-Deficient Narcolepsy.
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| 650 |
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|a Neurosciences.
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| 650 |
1 |
4 |
|a Neurosciences.
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| 700 |
1 |
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|a Nishino, Seiji.
|e editor.
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| 700 |
1 |
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|a Sakurai, Takeshi.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1385/1592599508
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