Target Discovery and Validation Reviews and Protocols Emerging Strategies for Targets and Biomarker Discovery, Volume 1 /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Sioud, Mouldy. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2007.
Edición:1st ed. 2007.
Colección:Methods in Molecular Biology, 360
Materias:
Acceso en línea:https://doi.org/10.1385/1597451657
Tabla de Contenidos:
  • Main Approaches to Target Discovery and Validation
  • Bioinformatics Approaches to Cancer Gene Discovery
  • Analysis of Gene Networks for Drug Target Discovery and Validation
  • Target Discovery and Validation in Pancreatic Cancer
  • Molecular Classification of Breast Tumors
  • Discovery of Differentially Expressed Genes
  • Genome-Wide Screening by Using Small-Interfering RNA-Expression Libraries
  • Hammerhead Ribozyme-Based Target Discovery
  • Production of siRNA and cDNA-Transfected Cell Arrays on Noncoated Chambered Coverglass for High-Content Screening Microscopy in Living Cells
  • Transgenic Animal Models in Biomedical Research
  • Keratin Transgenic and Knockout Mice
  • The HUVEC/Matrigel Assay
  • A Murine Model for Studying Hematopoiesis and Immunity in Heart Failure
  • An Overview of the Immune System and Technical Advances in Tumor Antigen Discovery and Validation
  • Potential Target Antigens for Immunotherapy Identified by Serological Expression Cloning (SEREX)
  • Identification of Tumor Antigens by Using Proteomics
  • Protein Arrays.