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02623nam a22003855i 4500 |
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978-1-59745-177-2 |
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20191026202652.0 |
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cr nn 008mamaa |
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100301s2008 xxu| s |||| 0|eng d |
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|a 9781597451772
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7 |
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|a 10.1007/978-1-59745-177-2
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a Molecular Modeling of Proteins
|c edited by Andreas Kukol.
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|a 1st ed. 2008.
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| 260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2008.
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| 300 |
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|a XII, 390 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 443
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|a Methodology -- Molecular Dynamics Simulations -- Monte Carlo Simulations -- Hybrid Quantum and Classical Methods for Computing Kinetic Isotope Effects of Chemical Reactions in Solutions and in Enzymes -- Comparison of Protein Force Fields for Molecular Dynamics Simulations -- Normal Modes and Essential Dynamics -- Free Energy Calculations -- Calculation of Absolute Protein-Ligand Binding Constants with the Molecular Dynamics Free Energy Perturbation Method -- Free Energy Calculations Applied to Membrane Proteins -- Molecular Modeling of Membrane Proteins -- Molecular Dynamics Simulations of Membrane Proteins -- Membrane-Associated Proteins and Peptides -- Implicit Membrane Models for Membrane Protein Simulation -- Protein Structure Determination -- Comparative Modeling of Proteins -- Transmembrane Protein Models Based on High-Throughput Molecular Dynamics Simulations with Experimental Constraints -- Nuclear Magnetic Resonance-Based Modeling and Refinement of Protein Three-Dimensional Structures and Their Complexes -- Conformational Change -- Conformational Changes in Protein Function -- Protein Folding and Unfolding by All-Atom Molecular Dynamics Simulations -- Modeling of Protein Misfolding in Disease -- Applications to Drug Design -- Identifying Putative Drug Targets and Potential Drug Leads -- Receptor Flexibility for Large-Scale In Silico Ligand Screens -- Molecular Docking.
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| 650 |
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|a Proteins .
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| 650 |
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|a Biochemistry.
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| 650 |
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|a Proteomics.
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| 650 |
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|a Molecular biology.
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| 650 |
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|a Bioinformatics.
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| 650 |
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4 |
|a Protein Science.
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| 650 |
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4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Proteomics.
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| 650 |
2 |
4 |
|a Molecular Medicine.
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| 650 |
2 |
4 |
|a Bioinformatics.
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| 700 |
1 |
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|a Kukol, Andreas.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-1-59745-177-2
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