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02522nam a22003135i 4500 |
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978-1-60327-575-0 |
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20191027062016.0 |
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cr nn 008mamaa |
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100301s2009 xxu| s |||| 0|eng d |
| 020 |
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|a 9781603275750
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| 024 |
7 |
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|a 10.1007/978-1-60327-575-0
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
4 |
|a The Nuclear Receptor Superfamily
|b Methods and Protocols /
|c edited by Iain J. McEwan.
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| 250 |
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|a 1st ed. 2009.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2009.
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| 300 |
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|a 240 p. 43 illus., 4 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 505
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| 505 |
0 |
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|a Nuclear Receptors: One Big Family -- Ligand Binding and Nuclear Receptor Turnover -- Methods for Measuring Ligand Dissociation and Nuclear Receptor Turnover in Whole Cells -- Flow Cytometry as a Tool for Measurement of Steroid Hormone Receptor Protein Expression in Leukocytes -- X-Ray Crystallography of Agonist/Antagonist-Bound Receptors -- Nuclear Localization and DNA Binding -- FRAP and FRET Methods to Study Nuclear Receptors in Living Cells -- Receptor-DNA Interactions: EMSA and Footprinting -- Chromatin Immunoprecipitation (ChIP) Methodology and Readouts -- Nuclear Receptor-Co-Regulatory Protein Interactions -- Yeast-Based Reporter Assays for the Functional Characterization of Cochaperone Interactions with Steroid Hormone Receptors -- High Throughput Analysis of Nuclear Receptor-Cofactor Interactions -- Binding Affinity and Kinetic Analysis of Nuclear Receptor/Co-Regulator Interactions Using Surface Plasmon Resonance -- Using RNA Interference to Study Protein Function -- Using Intrinsic Fluorescence Emission Spectroscopy to Study Steroid Receptor and Coactivator Protein Conformation Dynamics -- Pathophysiological Analysis of Nuclear Receptor Function -- Development of Phosphorylation Site-Specific Antibodies to Nuclear Receptors -- Tissue-Selective Knockouts of Steroid Receptors: A Novel Paradigm in the Study of Steroid Action -- Methods for Identifying and Studying Genetic Alterations in Hormone-Dependent Cancers.
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| 650 |
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|a Cell biology.
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| 650 |
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|a Gene expression.
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| 650 |
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4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Gene Expression.
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| 700 |
1 |
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|a McEwan, Iain J.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-1-60327-575-0
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